2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives
Quinoline is a privileged heterocyclic ring which can be found in many drug molecules and bioactive compounds. The development of synthetic methods for making quinoline derivatives continuously attracts the interest of organic and medicinal chemists. This paper highlights 2-azidobenzaldehyde-based [...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/29/6/1241 |
| _version_ | 1797239849516793856 |
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| author | Xiaofeng Zhang Miao Liu Weiqi Qiu Wei Zhang |
| author_facet | Xiaofeng Zhang Miao Liu Weiqi Qiu Wei Zhang |
| author_sort | Xiaofeng Zhang |
| collection | DOAJ |
| description | Quinoline is a privileged heterocyclic ring which can be found in many drug molecules and bioactive compounds. The development of synthetic methods for making quinoline derivatives continuously attracts the interest of organic and medicinal chemists. This paper highlights 2-azidobenzaldehyde-based [4+2] annulation for the synthesis of quinoline derivatives including fused and spiro-quinolines, quinoline-4-ols, 4-aminoquinolines, and related compounds. |
| first_indexed | 2024-04-24T17:58:04Z |
| format | Article |
| id | doaj.art-3044aaa650db413bafe65cf782de0850 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-24T17:58:04Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3044aaa650db413bafe65cf782de08502024-03-27T13:56:49ZengMDPI AGMolecules1420-30492024-03-01296124110.3390/molecules290612412-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline DerivativesXiaofeng Zhang0Miao Liu1Weiqi Qiu2Wei Zhang3Center for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA 02125, USACenter for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA 02125, USACenter for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA 02125, USACenter for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA 02125, USAQuinoline is a privileged heterocyclic ring which can be found in many drug molecules and bioactive compounds. The development of synthetic methods for making quinoline derivatives continuously attracts the interest of organic and medicinal chemists. This paper highlights 2-azidobenzaldehyde-based [4+2] annulation for the synthesis of quinoline derivatives including fused and spiro-quinolines, quinoline-4-ols, 4-aminoquinolines, and related compounds.https://www.mdpi.com/1420-3049/29/6/1241quinolinesazidobenzaldehyde[4+2] annulationheterocyclicbioactive |
| spellingShingle | Xiaofeng Zhang Miao Liu Weiqi Qiu Wei Zhang 2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives Molecules quinolines azidobenzaldehyde [4+2] annulation heterocyclic bioactive |
| title | 2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives |
| title_full | 2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives |
| title_fullStr | 2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives |
| title_full_unstemmed | 2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives |
| title_short | 2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives |
| title_sort | 2 azidobenzaldehyde based 4 2 annulation for the synthesis of quinoline derivatives |
| topic | quinolines azidobenzaldehyde [4+2] annulation heterocyclic bioactive |
| url | https://www.mdpi.com/1420-3049/29/6/1241 |
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