Advax-CpG Adjuvant Provides Antigen Dose-Sparing and Enhanced Immunogenicity for Inactivated Poliomyelitis Virus Vaccines

Advax-CpG Adjuvant Provides Antigen Dose-Sparing and Enhanced Immunogenicity for Inactivated Poliomyelitis Virus Vaccines

Global immunization campaigns have resulted in a major decline in the global incidence of polio cases, with wild-type poliovirus remaining endemic in only two countries. Live oral polio vaccine (OPV) played a role in the reduction in polio case numbers; however, the risk of OPV developing into circu...

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Bibliographic Details
Main Authors: Yoshikazu Honda-Okubo, Jeremy Baldwin, Nikolai Petrovsky
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pathogens
Subjects:
poliomyelitis
virus
vaccine
polio
adjuvant
Advax-CpG
Online Access:https://www.mdpi.com/2076-0817/10/5/500

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