The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypass

Autologous vein is the optimal conduit for peripheral arterial bypass surgery, a standard recently highlighted by findings from the BEST-CLI trial. The Human Acellular Vessel is a novel biologic conduit produced using regenerative medicine technologies with structural and mechanical properties like...

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Main Authors: Armin Farazdaghi, MD, Indrani Sen, MBBS, Peter B. Anderson, MD, Fahad Shuja, MBBS, Todd E. Rasmussen, MD
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468428723000321
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author Armin Farazdaghi, MD
Indrani Sen, MBBS
Peter B. Anderson, MD
Fahad Shuja, MBBS
Todd E. Rasmussen, MD
author_facet Armin Farazdaghi, MD
Indrani Sen, MBBS
Peter B. Anderson, MD
Fahad Shuja, MBBS
Todd E. Rasmussen, MD
author_sort Armin Farazdaghi, MD
collection DOAJ
description Autologous vein is the optimal conduit for peripheral arterial bypass surgery, a standard recently highlighted by findings from the BEST-CLI trial. The Human Acellular Vessel is a novel biologic conduit produced using regenerative medicine technologies with structural and mechanical properties like a human blood vessel. Not yet approved by the United States Food and Drug Administration, the Human Acellular Vessel is being studied as an alternative bypass conduit in patients with peripheral arterial disease, vascular injury, and those in need of arteriovenous access for hemodialysis. This report describes and illustrates the technical aspects of intraoperative handling specific to the use of this new and innovative technology.
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spelling doaj.art-3046e2cb8bd24829ac436dd5d907c9882023-09-27T04:43:30ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872023-09-0193101123The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypassArmin Farazdaghi, MD0Indrani Sen, MBBS1Peter B. Anderson, MD2Fahad Shuja, MBBS3Todd E. Rasmussen, MD4Division of Vascular and Endovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USAVascular and Endovascular Surgery, Mayo Clinic Health Systems, EauClaire, WIDivision of Vascular and Endovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USADivision of Vascular and Endovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USADivision of Vascular and Endovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA; Correspondence: Todd E. Rasmussen, MD, Division of Vascular and Endovascular Surgery, Mayo Clinic, 200 1st St SW, Rochester, MN 55905Autologous vein is the optimal conduit for peripheral arterial bypass surgery, a standard recently highlighted by findings from the BEST-CLI trial. The Human Acellular Vessel is a novel biologic conduit produced using regenerative medicine technologies with structural and mechanical properties like a human blood vessel. Not yet approved by the United States Food and Drug Administration, the Human Acellular Vessel is being studied as an alternative bypass conduit in patients with peripheral arterial disease, vascular injury, and those in need of arteriovenous access for hemodialysis. This report describes and illustrates the technical aspects of intraoperative handling specific to the use of this new and innovative technology.http://www.sciencedirect.com/science/article/pii/S2468428723000321Arterial reconstructionBioengineered vesselChronic limb-threatening ischemiaCritical limb-threatening ischemiaHAVHuman acellular vessel
spellingShingle Armin Farazdaghi, MD
Indrani Sen, MBBS
Peter B. Anderson, MD
Fahad Shuja, MBBS
Todd E. Rasmussen, MD
The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypass
Journal of Vascular Surgery Cases and Innovative Techniques
Arterial reconstruction
Bioengineered vessel
Chronic limb-threatening ischemia
Critical limb-threatening ischemia
HAV
Human acellular vessel
title The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypass
title_full The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypass
title_fullStr The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypass
title_full_unstemmed The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypass
title_short The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypass
title_sort human acellular vessel hav as a vascular conduit for infrainguinal arterial bypass
topic Arterial reconstruction
Bioengineered vessel
Chronic limb-threatening ischemia
Critical limb-threatening ischemia
HAV
Human acellular vessel
url http://www.sciencedirect.com/science/article/pii/S2468428723000321
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