Hemoglobin transfusion trigger in an internal medicine department - A "real world" six year experience.
Transfusion guidelines advocate restrictive rather than liberal use of red blood cells (RBC) and are based mostly on randomized trials in intensive care and surgical departments. We aimed to study RBC transfusion practice in the medical patients' population.The data in this study were collected...
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| Format: | Article |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5841806?pdf=render |
| _version_ | 1811236110824636416 |
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| author | Naomi Rahimi-Levene Tomer Ziv-Baran Victoria Peer Ahuva Golik Abraham Kornberg Ronit Zeidenstein Maya Koren-Michowitz |
| author_facet | Naomi Rahimi-Levene Tomer Ziv-Baran Victoria Peer Ahuva Golik Abraham Kornberg Ronit Zeidenstein Maya Koren-Michowitz |
| author_sort | Naomi Rahimi-Levene |
| collection | DOAJ |
| description | Transfusion guidelines advocate restrictive rather than liberal use of red blood cells (RBC) and are based mostly on randomized trials in intensive care and surgical departments. We aimed to study RBC transfusion practice in the medical patients' population.The data in this study were collected from patients over the age of 18 years admitted to an Internal Medicine department between 2009 and 2014 who received at least one unit of packed red blood cells (RBC). In addition, data on demographics, patients' diagnoses, laboratory tests and number of transfused RBC units were extracted from the electronic health records.One thousand three hundred and twenty eight patients were included, having mean age of 75 ± 14 years. The median hemoglobin (Hb) trigger for RBC transfusion was 8.0 g/dl (IQR 7.3-8.7g/dl), and most patients received either one (43.4%) or two (33.4%) RBC units. There was no significant difference in Hb trigger between males and females (Hb 8.0 g/dl and 7.9 g/dl, respectively, p = 0.098), and a weak correlation with age (r = 0.108 p = 0.001). Patients with cardiovascular and lung diseases had a statistically significant higher Hb trigger compared to patients without those diagnoses, however the median difference between them was 0.5 g/dl or less.These "real world" data we collected show a Hb trigger compliant with the upper limit of published guidelines and influenced by medical patients' common diagnoses. Prospective trials addressing patients hospitalized in internal medicine departments could further contribute to transfusion decision algorithms. |
| first_indexed | 2024-04-12T12:03:17Z |
| format | Article |
| id | doaj.art-3048f8e10e1a4c27b5b9fc3c2e311844 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T12:03:17Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-3048f8e10e1a4c27b5b9fc3c2e3118442022-12-22T03:33:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01133e019387310.1371/journal.pone.0193873Hemoglobin transfusion trigger in an internal medicine department - A "real world" six year experience.Naomi Rahimi-LeveneTomer Ziv-BaranVictoria PeerAhuva GolikAbraham KornbergRonit ZeidensteinMaya Koren-MichowitzTransfusion guidelines advocate restrictive rather than liberal use of red blood cells (RBC) and are based mostly on randomized trials in intensive care and surgical departments. We aimed to study RBC transfusion practice in the medical patients' population.The data in this study were collected from patients over the age of 18 years admitted to an Internal Medicine department between 2009 and 2014 who received at least one unit of packed red blood cells (RBC). In addition, data on demographics, patients' diagnoses, laboratory tests and number of transfused RBC units were extracted from the electronic health records.One thousand three hundred and twenty eight patients were included, having mean age of 75 ± 14 years. The median hemoglobin (Hb) trigger for RBC transfusion was 8.0 g/dl (IQR 7.3-8.7g/dl), and most patients received either one (43.4%) or two (33.4%) RBC units. There was no significant difference in Hb trigger between males and females (Hb 8.0 g/dl and 7.9 g/dl, respectively, p = 0.098), and a weak correlation with age (r = 0.108 p = 0.001). Patients with cardiovascular and lung diseases had a statistically significant higher Hb trigger compared to patients without those diagnoses, however the median difference between them was 0.5 g/dl or less.These "real world" data we collected show a Hb trigger compliant with the upper limit of published guidelines and influenced by medical patients' common diagnoses. Prospective trials addressing patients hospitalized in internal medicine departments could further contribute to transfusion decision algorithms.http://europepmc.org/articles/PMC5841806?pdf=render |
| spellingShingle | Naomi Rahimi-Levene Tomer Ziv-Baran Victoria Peer Ahuva Golik Abraham Kornberg Ronit Zeidenstein Maya Koren-Michowitz Hemoglobin transfusion trigger in an internal medicine department - A "real world" six year experience. PLoS ONE |
| title | Hemoglobin transfusion trigger in an internal medicine department - A "real world" six year experience. |
| title_full | Hemoglobin transfusion trigger in an internal medicine department - A "real world" six year experience. |
| title_fullStr | Hemoglobin transfusion trigger in an internal medicine department - A "real world" six year experience. |
| title_full_unstemmed | Hemoglobin transfusion trigger in an internal medicine department - A "real world" six year experience. |
| title_short | Hemoglobin transfusion trigger in an internal medicine department - A "real world" six year experience. |
| title_sort | hemoglobin transfusion trigger in an internal medicine department a real world six year experience |
| url | http://europepmc.org/articles/PMC5841806?pdf=render |
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