The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates

The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates

Bacteroidetes feature prominently in the human microbiome, as major colonizers of the gut and clinically relevant pathogens elsewhere. Here, we reveal a new Bacteroidetes specific feature in the otherwise widely conserved Sec/SPI (Sec translocase/signal peptidase I) pathway. In Bacteroidetes, but no...

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Bibliographic Details
Main Authors: Matthias Bochtler, Danuta Mizgalska, Florian Veillard, Magdalena L. Nowak, John Houston, Paul Veith, Eric C. Reynolds, Jan Potempa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Microbiology
Subjects:
Bacteroidetes
signal peptidase I
glutaminyl cyclase
pyroglutamate
Porphyromonas
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00230/full

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