Dystrophin-deficient cardiomyocytes derived from human urine: New biologic reagents for drug discovery

Dystrophin-deficient cardiomyocytes derived from human urine: New biologic reagents for drug discovery

The ability to extract somatic cells from a patient and reprogram them to pluripotency opens up new possibilities for personalized medicine. Induced pluripotent stem cells (iPSCs) have been employed to generate beating cardiomyocytes from a patient's skin or blood cells. Here, iPSC methods were...

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Bibliographic Details
Main Authors: Xuan Guan, David L. Mack, Claudia M. Moreno, Jennifer L. Strande, Julie Mathieu, Yingai Shi, Chad D. Markert, Zejing Wang, Guihua Liu, Michael W. Lawlor, Emily C. Moorefield, Tara N. Jones, James A. Fugate, Mark E. Furth, Charles E. Murry, Hannele Ruohola-Baker, Yuanyuan Zhang, Luis F. Santana, Martin K. Childers
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506113001827

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