Co-amorphization of Ibuprofen by Paracetamol for Improved Processability, Solubility, and In vitro Dissolution.

Co-amorphization of Ibuprofen by Paracetamol for Improved Processability, Solubility, and In vitro Dissolution.

Co-amorphous (COAM) systems of ibuprofen (IB) and paracetamol (PA), in clinical dose ratios, were prepared by ball milling to enhance solubility and dissolution of IB. Subsequently, COAM were characterized by solubility, processability, XRPD, DSC, ATR-FTIR, SEM, in-vitro dissolution and accelerated...

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Bibliographic Details
Main Authors:	Mayuri S. Bhandari, Sarika M. Wairkar, Udaykumar S. Patil, Namdeo R Jadhav
Format:	Article
Language:	English
Published:	Slovenian Chemical Society 2018-09-01
Series:	Acta Chimica Slovenica
Subjects:	Ibuprofen co-amorphism with paracetamol improved processability solubility and dissolution of ibuprofen.
Online Access:	https://journals.matheo.si/index.php/ACSi/article/view/3822

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