Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark
Reported for its antioxidant, anti-inflammatory and non-toxicity properties, the hot water extract of Picea mariana bark was demonstrated to contain highly valuable bioactive polyphenols. In order to improve the recovery of these molecules, an optimization of the extraction was performed using water...
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| Format: | Article |
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MDPI AG
2017-12-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/22/12/2118 |
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| author | Nellie Francezon Naamwin-So-Bâwfu Romaric Meda Tatjana Stevanovic |
| author_facet | Nellie Francezon Naamwin-So-Bâwfu Romaric Meda Tatjana Stevanovic |
| author_sort | Nellie Francezon |
| collection | DOAJ |
| description | Reported for its antioxidant, anti-inflammatory and non-toxicity properties, the hot water extract of Picea mariana bark was demonstrated to contain highly valuable bioactive polyphenols. In order to improve the recovery of these molecules, an optimization of the extraction was performed using water. Several extraction parameters were tested and extracts obtained analyzed both in terms of relative amounts of different phytochemical families and of individual molecules concentrations. As a result, low temperature (80 °C) and low ratio of bark/water (50 mg/mL) were determined to be the best parameters for an efficient polyphenol extraction and that especially for low molecular mass polyphenols. These were identified as stilbene monomers and derivatives, mainly stilbene glucoside isorhapontin (up to 12.0% of the dry extract), astringin (up to 4.6%), resveratrol (up to 0.3%), isorhapontigenin (up to 3.7%) and resveratrol glucoside piceid (up to 3.1%) which is here reported for the first time for Picea mariana. New stilbene derivatives, piceasides O and P were also characterized herein as new isorhapontin dimers. This study provides novel information about the optimal extraction of polyphenols from black spruce bark, especially for highly bioactive stilbenes including the trans-resveratrol. |
| first_indexed | 2024-12-14T13:30:57Z |
| format | Article |
| id | doaj.art-305a98a79de2413e8c786d6d7b44f491 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-14T13:30:57Z |
| publishDate | 2017-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-305a98a79de2413e8c786d6d7b44f4912022-12-21T22:59:43ZengMDPI AGMolecules1420-30492017-12-012212211810.3390/molecules22122118molecules22122118Optimization of Bioactive Polyphenols Extraction from Picea Mariana BarkNellie Francezon0Naamwin-So-Bâwfu Romaric Meda1Tatjana Stevanovic2Renewable Materials Research Centre, Department of Wood and Forest Sciences, Université Laval, Québec, QC G1V 0A6, CanadaRenewable Materials Research Centre, Department of Wood and Forest Sciences, Université Laval, Québec, QC G1V 0A6, CanadaRenewable Materials Research Centre, Department of Wood and Forest Sciences, Université Laval, Québec, QC G1V 0A6, CanadaReported for its antioxidant, anti-inflammatory and non-toxicity properties, the hot water extract of Picea mariana bark was demonstrated to contain highly valuable bioactive polyphenols. In order to improve the recovery of these molecules, an optimization of the extraction was performed using water. Several extraction parameters were tested and extracts obtained analyzed both in terms of relative amounts of different phytochemical families and of individual molecules concentrations. As a result, low temperature (80 °C) and low ratio of bark/water (50 mg/mL) were determined to be the best parameters for an efficient polyphenol extraction and that especially for low molecular mass polyphenols. These were identified as stilbene monomers and derivatives, mainly stilbene glucoside isorhapontin (up to 12.0% of the dry extract), astringin (up to 4.6%), resveratrol (up to 0.3%), isorhapontigenin (up to 3.7%) and resveratrol glucoside piceid (up to 3.1%) which is here reported for the first time for Picea mariana. New stilbene derivatives, piceasides O and P were also characterized herein as new isorhapontin dimers. This study provides novel information about the optimal extraction of polyphenols from black spruce bark, especially for highly bioactive stilbenes including the trans-resveratrol.https://www.mdpi.com/1420-3049/22/12/2118Picea marianabarkhot water extractionchemometricsstilbenespiceaside |
| spellingShingle | Nellie Francezon Naamwin-So-Bâwfu Romaric Meda Tatjana Stevanovic Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark Molecules Picea mariana bark hot water extraction chemometrics stilbenes piceaside |
| title | Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark |
| title_full | Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark |
| title_fullStr | Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark |
| title_full_unstemmed | Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark |
| title_short | Optimization of Bioactive Polyphenols Extraction from Picea Mariana Bark |
| title_sort | optimization of bioactive polyphenols extraction from picea mariana bark |
| topic | Picea mariana bark hot water extraction chemometrics stilbenes piceaside |
| url | https://www.mdpi.com/1420-3049/22/12/2118 |
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