Sensitivity and specificity of 24-hour-delayed radiographs in demonstrating the transition zone of Hirschsprung disease

Objective: Our aims were to determine the sensitivity and specificity of the practice of 24-hour-delayed radiographs used to demonstrate the transition zone of Hirschsprung disease. Materials and Methods: We collected the cases from all pediatric patients with suspected Hirschsprung disease who were...

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Main Authors: Teeranan Laohawiriyakamol, Pramot Tanutit
Format: Article
Language:English
Published: Prince of Songkla University 2010-02-01
Series:Journal of Health Science and Medical Research (JHSMR)
Subjects:
Online Access:https://www.jhsmr.org/index.php/jhsmr/article/view/334
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author Teeranan Laohawiriyakamol
Pramot Tanutit
author_facet Teeranan Laohawiriyakamol
Pramot Tanutit
author_sort Teeranan Laohawiriyakamol
collection DOAJ
description Objective: Our aims were to determine the sensitivity and specificity of the practice of 24-hour-delayed radiographs used to demonstrate the transition zone of Hirschsprung disease. Materials and Methods: We collected the cases from all pediatric patients with suspected Hirschsprung disease who were referred for barium enema with a 24-hour-delayed radiographs from January 2000 through October 2006. All pediatric patients had a final biopsy diagnosis. Both barium enema and 24-hour-delayed radiographs were restudied by an experienced radiologist unaware of the results of the pathology reports. The radiologist used a checklist of radiological criteria including transition zone, rectosigmoid index and mucosal irregularity patterns on barium enema and retention of contrast agent on delayed radiographs. The sensitivity and specificity of the findings were evaluated using 2x2 tables. Results:The study had 46 patients, 27 with and 19 without Hirschsprung disease. The sensitivity and specificity of the 24-hour-delayed radiographs for demonstrating the transition zone of Hirschsprung disease were about 80.8 and 40.0 percent, respectively. The sensitivity andspecificity of barium enema for demonstrating the transition zone of Hirschsprung disease were about 88.9 percent and 36.8 percent, respectively. Conclusion: 24-hour-delayed radiographs had high sensitivity and low specificity for demonstrating the transition zone of Hirschsprung disease, about the same as a barium enema.
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spelling doaj.art-30636ab3625944e9af9902a6194a564e2022-12-22T01:24:02ZengPrince of Songkla UniversityJournal of Health Science and Medical Research (JHSMR)2586-99812630-05592010-02-0128117348Sensitivity and specificity of 24-hour-delayed radiographs in demonstrating the transition zone of Hirschsprung diseaseTeeranan Laohawiriyakamol0Pramot Tanutit1Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,Objective: Our aims were to determine the sensitivity and specificity of the practice of 24-hour-delayed radiographs used to demonstrate the transition zone of Hirschsprung disease. Materials and Methods: We collected the cases from all pediatric patients with suspected Hirschsprung disease who were referred for barium enema with a 24-hour-delayed radiographs from January 2000 through October 2006. All pediatric patients had a final biopsy diagnosis. Both barium enema and 24-hour-delayed radiographs were restudied by an experienced radiologist unaware of the results of the pathology reports. The radiologist used a checklist of radiological criteria including transition zone, rectosigmoid index and mucosal irregularity patterns on barium enema and retention of contrast agent on delayed radiographs. The sensitivity and specificity of the findings were evaluated using 2x2 tables. Results:The study had 46 patients, 27 with and 19 without Hirschsprung disease. The sensitivity and specificity of the 24-hour-delayed radiographs for demonstrating the transition zone of Hirschsprung disease were about 80.8 and 40.0 percent, respectively. The sensitivity andspecificity of barium enema for demonstrating the transition zone of Hirschsprung disease were about 88.9 percent and 36.8 percent, respectively. Conclusion: 24-hour-delayed radiographs had high sensitivity and low specificity for demonstrating the transition zone of Hirschsprung disease, about the same as a barium enema.https://www.jhsmr.org/index.php/jhsmr/article/view/33424-hour-delayed radiographshirschsprung diseasetransition zone
spellingShingle Teeranan Laohawiriyakamol
Pramot Tanutit
Sensitivity and specificity of 24-hour-delayed radiographs in demonstrating the transition zone of Hirschsprung disease
Journal of Health Science and Medical Research (JHSMR)
24-hour-delayed radiographs
hirschsprung disease
transition zone
title Sensitivity and specificity of 24-hour-delayed radiographs in demonstrating the transition zone of Hirschsprung disease
title_full Sensitivity and specificity of 24-hour-delayed radiographs in demonstrating the transition zone of Hirschsprung disease
title_fullStr Sensitivity and specificity of 24-hour-delayed radiographs in demonstrating the transition zone of Hirschsprung disease
title_full_unstemmed Sensitivity and specificity of 24-hour-delayed radiographs in demonstrating the transition zone of Hirschsprung disease
title_short Sensitivity and specificity of 24-hour-delayed radiographs in demonstrating the transition zone of Hirschsprung disease
title_sort sensitivity and specificity of 24 hour delayed radiographs in demonstrating the transition zone of hirschsprung disease
topic 24-hour-delayed radiographs
hirschsprung disease
transition zone
url https://www.jhsmr.org/index.php/jhsmr/article/view/334
work_keys_str_mv AT teerananlaohawiriyakamol sensitivityandspecificityof24hourdelayedradiographsindemonstratingthetransitionzoneofhirschsprungdisease
AT pramottanutit sensitivityandspecificityof24hourdelayedradiographsindemonstratingthetransitionzoneofhirschsprungdisease