Mediator-Related Symptoms and Anaphylaxis in Children with Mastocytosis

Mediator-Related Symptoms and Anaphylaxis in Children with Mastocytosis

Mastocytosis is characterized by the pathological accumulation of mast cells (MC) in various organs. In these patients, MC may degranulate and thereby contribute to clinical symptoms, especially when a concomitant allergy is present. However, MC activation can not only be induced by high-affinity re...

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Bibliographic Details
Main Authors: Knut Brockow, Katarzyna Plata-Nazar, Magdalena Lange, Bogusław Nedoszytko, Marek Niedoszytko, Peter Valent
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
mast cells
mastocytosis
mediator-related symptoms
anaphylaxis
children
Online Access:https://www.mdpi.com/1422-0067/22/5/2684

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