Effect of Sodium Arsenite on the Expression of Antioxidant Genes (SOD2 and CAT) in MCF-7 and Jurkat Cell Lines

Effect of Sodium Arsenite on the Expression of Antioxidant Genes (SOD2 and CAT) in MCF-7 and Jurkat Cell Lines

Background: Sodium arsenite (NaAsO2) has potent cytotoxic activity in human cancer cells. Oxidative stress has been suggested as a mechanism for arsenic-induced carcinogenesis. The purpose of the present study was to evaluate the alteration of mRNA levels of catalase (CAT) and superoxide dismutase 2...

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Bibliographic Details
Main Authors: Leila FALLAHZADEH-ABARGHOOEI, Maryam SAMADAEI-GHADIKOLAIE, Iraj SAADAT, Mostafa SAADAT
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-02-01
Series:Iranian Journal of Public Health
Subjects:
Catalase
mRNA
N-acetyl-cysteine
SOD2
Sodium arsenite
MCF-7 cells
Online Access:https://ijph.tums.ac.ir/index.php/ijph/article/view/9053

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