A rare case of uterine leiomyosarcoma: a case report

<p>Abstract</p> <p>Introduction</p> <p>Malignant change in a leiomyoma or uterine fibroid is termed <it>leiomyosarcoma</it>. It arises from smooth muscle of the uterus and is a rare tumor that accounts for 2% to 5% of all uterine malignancies. Very few cases...

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Main Authors: Chinamotu Rao N, Sunkavalli Chinna, Rao Meghana, Vellanki Venkata, Kaja Shailaja
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Journal of Medical Case Reports
Online Access:http://www.jmedicalcasereports.com/content/4/1/222
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author Chinamotu Rao N
Sunkavalli Chinna
Rao Meghana
Vellanki Venkata
Kaja Shailaja
author_facet Chinamotu Rao N
Sunkavalli Chinna
Rao Meghana
Vellanki Venkata
Kaja Shailaja
author_sort Chinamotu Rao N
collection DOAJ
description <p>Abstract</p> <p>Introduction</p> <p>Malignant change in a leiomyoma or uterine fibroid is termed <it>leiomyosarcoma</it>. It arises from smooth muscle of the uterus and is a rare tumor that accounts for 2% to 5% of all uterine malignancies. Very few cases are reported in the literature. Our patient did not have any history of genital bleeding, which is the usual presentation in uterine sarcoma. We report an original case report of an unusual presentation of this rare tumor arising from the uterus.</p> <p>Case presentation</p> <p>A 40-year-old nulliparous woman of South Indian origin presented with a mass in her abdomen for one year with a rapid increase in size over the previous three months. Tumor marker CA-125 was raised, and a computed tomography scan showed a mass arising from the pelvis. An exploratory laparotomy was performed and the histopathology report confirmed the diagnosis of uterine leiomyosarcoma.</p> <p>Conclusion</p> <p>Because of their rarity, uterine sarcomas are not suitable for screening. Diagnosis is by histopathologic examination and surgery is the only treatment. The prognosis for women with uterine sarcoma primarily depends on the extent of disease at the time of diagnosis and the mitotic index.</p>
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spelling doaj.art-30690645e77a4d6ca260f6f10f8e33322022-12-22T02:40:42ZengBMCJournal of Medical Case Reports1752-19472010-07-014122210.1186/1752-1947-4-222A rare case of uterine leiomyosarcoma: a case reportChinamotu Rao NSunkavalli ChinnaRao MeghanaVellanki VenkataKaja Shailaja<p>Abstract</p> <p>Introduction</p> <p>Malignant change in a leiomyoma or uterine fibroid is termed <it>leiomyosarcoma</it>. It arises from smooth muscle of the uterus and is a rare tumor that accounts for 2% to 5% of all uterine malignancies. Very few cases are reported in the literature. Our patient did not have any history of genital bleeding, which is the usual presentation in uterine sarcoma. We report an original case report of an unusual presentation of this rare tumor arising from the uterus.</p> <p>Case presentation</p> <p>A 40-year-old nulliparous woman of South Indian origin presented with a mass in her abdomen for one year with a rapid increase in size over the previous three months. Tumor marker CA-125 was raised, and a computed tomography scan showed a mass arising from the pelvis. An exploratory laparotomy was performed and the histopathology report confirmed the diagnosis of uterine leiomyosarcoma.</p> <p>Conclusion</p> <p>Because of their rarity, uterine sarcomas are not suitable for screening. Diagnosis is by histopathologic examination and surgery is the only treatment. The prognosis for women with uterine sarcoma primarily depends on the extent of disease at the time of diagnosis and the mitotic index.</p>http://www.jmedicalcasereports.com/content/4/1/222
spellingShingle Chinamotu Rao N
Sunkavalli Chinna
Rao Meghana
Vellanki Venkata
Kaja Shailaja
A rare case of uterine leiomyosarcoma: a case report
Journal of Medical Case Reports
title A rare case of uterine leiomyosarcoma: a case report
title_full A rare case of uterine leiomyosarcoma: a case report
title_fullStr A rare case of uterine leiomyosarcoma: a case report
title_full_unstemmed A rare case of uterine leiomyosarcoma: a case report
title_short A rare case of uterine leiomyosarcoma: a case report
title_sort rare case of uterine leiomyosarcoma a case report
url http://www.jmedicalcasereports.com/content/4/1/222
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