Evaluation of atherosclerosis as a risk factor in COPD patients by measuring the carotid intima-media thickness
Abstract Background This study aimed to evaluate atherosclerosis as comorbidity by measuring the carotid (bulb and common carotid artery) Carotid intima-media thickness in COPD-diagnosed patients and to evaluate the relationship of atherosclerosis with the prevalence of COPD, hypoxemia and hypercapn...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | Cardiovascular Ultrasound |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12947-023-00322-8 |
| _version_ | 1827382394481541120 |
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| author | Ali Firincioglulari Hakan Erturk Mujgan Firincioglulari Cigdem Biber |
| author_facet | Ali Firincioglulari Hakan Erturk Mujgan Firincioglulari Cigdem Biber |
| author_sort | Ali Firincioglulari |
| collection | DOAJ |
| description | Abstract Background This study aimed to evaluate atherosclerosis as comorbidity by measuring the carotid (bulb and common carotid artery) Carotid intima-media thickness in COPD-diagnosed patients and to evaluate the relationship of atherosclerosis with the prevalence of COPD, hypoxemia and hypercapnia. Methods This study was conducted out between January 2019-December 2019 consisting of a total of 140 participants (70 COPD-diagnosed patients-70 healthy individuals). The COPD-diagnosed patients have been planned according to the selection and diagnosis criteria as per the GOLD 2019 guide. It is planned to evaluate as per prospective matching case-control study of the carotid thickness, radial gas analysis, spirometric and demographic characteristics of COPD diagnosed patients and healthy individuals. Results The average Carotid intima-media thickness in COPD patients was 0.8746±0.161 (p<0.05), and the thickness of the carotid bulb was 1.04±0.150 (p<0.05). In the control group, the average CCA intima-media thickness was 0.6650±0.139 (p<0.05), and the thickness of the carotid bulb was 0.8250±0.15(p<0.05) For the carotid thickness that has increased in COPD diagnosed patients a significant relationship is determined between hypoxemia (p<0.05) and hypercapnia(p<0.05). A significant relationship determined between CIMT and severity of COPD (p<0.05) The CIMT was high in COPD patients with hypoxemia and hypercapnia(p<0.05). Conclusion Significant difference was determined between the severity (grades) of COPD (mild, moderate, severe, very severe) in carotid thickness. Also, CIMT was found to be high in patients who is in the early phases of the prevalence of COPD. In COPD-diagnosed patients, it was determined that severity of COPD, hypoxemia, hypercapnia and age were determining factors of atherosclerosis. Graphical Abstract |
| first_indexed | 2024-03-08T14:18:55Z |
| format | Article |
| id | doaj.art-306a312d0e06412bb8411dbff137399f |
| institution | Directory Open Access Journal |
| issn | 1476-7120 |
| language | English |
| last_indexed | 2024-03-08T14:18:55Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Cardiovascular Ultrasound |
| spelling | doaj.art-306a312d0e06412bb8411dbff137399f2024-01-14T12:13:28ZengBMCCardiovascular Ultrasound1476-71202024-01-0122111310.1186/s12947-023-00322-8Evaluation of atherosclerosis as a risk factor in COPD patients by measuring the carotid intima-media thicknessAli Firincioglulari0Hakan Erturk1Mujgan Firincioglulari2Cigdem Biber3Department of Chest Diseases, Dr Burhan Nalbantoğlu State HospitalDepartment of Radiology, Health Sciences University, Ankara Atatürk Sanatoryum Training and Research HospitalFaculty of Dentistry, Department of Dentomaxillofacial Radiology, Cyprus International UniversityDepartment of Chest Diseases, Health Sciences University, Ankara Atatürk Sanatoryum Training and Research HospitalAbstract Background This study aimed to evaluate atherosclerosis as comorbidity by measuring the carotid (bulb and common carotid artery) Carotid intima-media thickness in COPD-diagnosed patients and to evaluate the relationship of atherosclerosis with the prevalence of COPD, hypoxemia and hypercapnia. Methods This study was conducted out between January 2019-December 2019 consisting of a total of 140 participants (70 COPD-diagnosed patients-70 healthy individuals). The COPD-diagnosed patients have been planned according to the selection and diagnosis criteria as per the GOLD 2019 guide. It is planned to evaluate as per prospective matching case-control study of the carotid thickness, radial gas analysis, spirometric and demographic characteristics of COPD diagnosed patients and healthy individuals. Results The average Carotid intima-media thickness in COPD patients was 0.8746±0.161 (p<0.05), and the thickness of the carotid bulb was 1.04±0.150 (p<0.05). In the control group, the average CCA intima-media thickness was 0.6650±0.139 (p<0.05), and the thickness of the carotid bulb was 0.8250±0.15(p<0.05) For the carotid thickness that has increased in COPD diagnosed patients a significant relationship is determined between hypoxemia (p<0.05) and hypercapnia(p<0.05). A significant relationship determined between CIMT and severity of COPD (p<0.05) The CIMT was high in COPD patients with hypoxemia and hypercapnia(p<0.05). Conclusion Significant difference was determined between the severity (grades) of COPD (mild, moderate, severe, very severe) in carotid thickness. Also, CIMT was found to be high in patients who is in the early phases of the prevalence of COPD. In COPD-diagnosed patients, it was determined that severity of COPD, hypoxemia, hypercapnia and age were determining factors of atherosclerosis. Graphical Abstracthttps://doi.org/10.1186/s12947-023-00322-8COPDAtherosclerosisStrokeCIMTCarotid Bulbus |
| spellingShingle | Ali Firincioglulari Hakan Erturk Mujgan Firincioglulari Cigdem Biber Evaluation of atherosclerosis as a risk factor in COPD patients by measuring the carotid intima-media thickness Cardiovascular Ultrasound COPD Atherosclerosis Stroke CIMT Carotid Bulbus |
| title | Evaluation of atherosclerosis as a risk factor in COPD patients by measuring the carotid intima-media thickness |
| title_full | Evaluation of atherosclerosis as a risk factor in COPD patients by measuring the carotid intima-media thickness |
| title_fullStr | Evaluation of atherosclerosis as a risk factor in COPD patients by measuring the carotid intima-media thickness |
| title_full_unstemmed | Evaluation of atherosclerosis as a risk factor in COPD patients by measuring the carotid intima-media thickness |
| title_short | Evaluation of atherosclerosis as a risk factor in COPD patients by measuring the carotid intima-media thickness |
| title_sort | evaluation of atherosclerosis as a risk factor in copd patients by measuring the carotid intima media thickness |
| topic | COPD Atherosclerosis Stroke CIMT Carotid Bulbus |
| url | https://doi.org/10.1186/s12947-023-00322-8 |
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