Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event
The presence of adipocytes within thyroid glands is a rare finding seen in thyrolipoma, diffuse lipomatosis, or thyroid teratoma. Although some cases present with multinodular goiter or autoimmune thyroiditis, the exact cause has not yet been elucidated. Among reported cases, thyrolipomas mainly occ...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/8/1334 |
| _version_ | 1797524155219836928 |
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| author | Mariya Kuk Chu-Jen Kuo Van-Hung Nguyen Chien-Chin Chen |
| author_facet | Mariya Kuk Chu-Jen Kuo Van-Hung Nguyen Chien-Chin Chen |
| author_sort | Mariya Kuk |
| collection | DOAJ |
| description | The presence of adipocytes within thyroid glands is a rare finding seen in thyrolipoma, diffuse lipomatosis, or thyroid teratoma. Although some cases present with multinodular goiter or autoimmune thyroiditis, the exact cause has not yet been elucidated. Among reported cases, thyrolipomas mainly occur in females and usually present as a solitary lesion. However, a few reported cases had coexisting papillary thyroid carcinomas. Herein, we present a 51-year-old female with synchronous thyrolipoma (2.0 × 1.5 × 1.3 cm) and papillary thyroid carcinoma (0.7 × 0.6 × 0.6 cm) within the same thyroid lobe. She had diabetes mellitus and hypertension and complained of anterior neck enlargement and discomfort for three months. Thyroid sonography showed multiple hypoechoic nodules, one of which was heterogeneous and ill-defined. Fine needle aspirate cytology for the ill-defined nodule was suspicious for papillary thyroid carcinoma. She subsequently received radical thyroidectomy and neck lymph node dissection. Histopathologically, one thyrolipoma and one papillary thyroid carcinoma were identified in the right lobe of the thyroid gland without metastases of lymph nodes, while other nodules were multinodular goiter. Notably, thyrolipoma may not be simply an incidental finding but might coexist with thyroid carcinomas. A brief review of the pertinent literature of prior reports is also provided. |
| first_indexed | 2024-03-10T08:53:22Z |
| format | Article |
| id | doaj.art-306b7ab870024c91a9f633f998dd0e07 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T08:53:22Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-306b7ab870024c91a9f633f998dd0e072023-11-22T07:19:01ZengMDPI AGDiagnostics2075-44182021-07-01118133410.3390/diagnostics11081334Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant EventMariya Kuk0Chu-Jen Kuo1Van-Hung Nguyen2Chien-Chin Chen3Department of Pathology, Montreal Children’s Hospital, McGill University Health Centre, Montreal, QC H4A 3J1, CanadaDepartment of Radiology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi 600, TaiwanDepartment of Pathology, Montreal Children’s Hospital, McGill University Health Centre, Montreal, QC H4A 3J1, CanadaDepartment of Pathology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi 600, TaiwanThe presence of adipocytes within thyroid glands is a rare finding seen in thyrolipoma, diffuse lipomatosis, or thyroid teratoma. Although some cases present with multinodular goiter or autoimmune thyroiditis, the exact cause has not yet been elucidated. Among reported cases, thyrolipomas mainly occur in females and usually present as a solitary lesion. However, a few reported cases had coexisting papillary thyroid carcinomas. Herein, we present a 51-year-old female with synchronous thyrolipoma (2.0 × 1.5 × 1.3 cm) and papillary thyroid carcinoma (0.7 × 0.6 × 0.6 cm) within the same thyroid lobe. She had diabetes mellitus and hypertension and complained of anterior neck enlargement and discomfort for three months. Thyroid sonography showed multiple hypoechoic nodules, one of which was heterogeneous and ill-defined. Fine needle aspirate cytology for the ill-defined nodule was suspicious for papillary thyroid carcinoma. She subsequently received radical thyroidectomy and neck lymph node dissection. Histopathologically, one thyrolipoma and one papillary thyroid carcinoma were identified in the right lobe of the thyroid gland without metastases of lymph nodes, while other nodules were multinodular goiter. Notably, thyrolipoma may not be simply an incidental finding but might coexist with thyroid carcinomas. A brief review of the pertinent literature of prior reports is also provided.https://www.mdpi.com/2075-4418/11/8/1334adenolipomacytologyfine needle aspirationlipomapapillary thyroid cancerthyroid |
| spellingShingle | Mariya Kuk Chu-Jen Kuo Van-Hung Nguyen Chien-Chin Chen Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event Diagnostics adenolipoma cytology fine needle aspiration lipoma papillary thyroid cancer thyroid |
| title | Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event |
| title_full | Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event |
| title_fullStr | Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event |
| title_full_unstemmed | Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event |
| title_short | Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event |
| title_sort | synchronous thyrolipoma and papillary thyroid carcinoma a rare but significant event |
| topic | adenolipoma cytology fine needle aspiration lipoma papillary thyroid cancer thyroid |
| url | https://www.mdpi.com/2075-4418/11/8/1334 |
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