Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria
Background: This study determined current status of laboratory biosafety in Nigerian veterinary research facilities. Methods: A questionnaire was developed to obtain information from researchers across Nigeria from July 2014 to July 2015. Information regarding demographics, knowledge of laboratory b...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-03-01
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| Series: | Safety and Health at Work |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2093791116301275 |
| _version_ | 1797714484948631552 |
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| author | Ismail Ayoade Odetokun Afusat Toyin Jagun-Jubril Bernard A. Onoja Yiltawe Simwal Wungak Ibrahim Adisa Raufu Jessica Corron Chen |
| author_facet | Ismail Ayoade Odetokun Afusat Toyin Jagun-Jubril Bernard A. Onoja Yiltawe Simwal Wungak Ibrahim Adisa Raufu Jessica Corron Chen |
| author_sort | Ismail Ayoade Odetokun |
| collection | DOAJ |
| description | Background: This study determined current status of laboratory biosafety in Nigerian veterinary research facilities.
Methods: A questionnaire was developed to obtain information from researchers across Nigeria from July 2014 to July 2015. Information regarding demographics, knowledge of laboratory biosafety, availability and proper use of personal protective equipment (PPE), any priority pathogens researched, attitude on and use of standard laboratory practices, and biosafety awareness was obtained using a numeric scoring system. Data were analyzed with descriptive statistics, and univariate and multivariate logistic regression.
Results: A total of 74 participants from 19 facilities completed the questionnaire. General knowledge scores ranged from 3 to 28 (out of 28 possible points), with 94.6% of respondents receiving low scores (scores < mean + 1 standard deviation). Very few (17.6%) reported availability or use PPE. Many participants (63.5%) reported no access to biosafety level (BSL)-1–3 facilities. None reported availability of a BSL-4 facility. Knowledge scores pertaining to biosafety management practices ranged from 0 to 14 (out of 14 possible points) with 47.3% of respondents receiving good scores (scores > mean + 1 standard deviation). Only 16.2% of respondents (from four facilities) reported having biosafety officers. Rabies virus was the most researched pathogen (31.1% of respondents). The majority (71.6%) were unaware of laws guiding biosafety. Researchers [odds ratio (OR) = 18.0; 95% confidence interval (CI): 1.63, 198.5; p = 0.023], especially in BSL-2 (OR = 258.5; 95% CI: 12.71, 5256; p < 0.001) facility of research institute (OR = 25.0; 95% CI: 5.18, 120.6; p < 0.001), are more likely to have adequate access to and properly utilize biosafety devices and PPE.
Conclusions: Current knowledge of laboratory biosafety is limited except among a few researchers. |
| first_indexed | 2024-03-12T07:52:39Z |
| format | Article |
| id | doaj.art-306c13d7570a41b595ccd95b4246bef1 |
| institution | Directory Open Access Journal |
| issn | 2093-7911 |
| language | English |
| last_indexed | 2024-03-12T07:52:39Z |
| publishDate | 2017-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Safety and Health at Work |
| spelling | doaj.art-306c13d7570a41b595ccd95b4246bef12023-09-02T20:29:32ZengElsevierSafety and Health at Work2093-79112017-03-0181495810.1016/j.shaw.2016.08.002Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in NigeriaIsmail Ayoade Odetokun0Afusat Toyin Jagun-Jubril1Bernard A. Onoja2Yiltawe Simwal Wungak3Ibrahim Adisa Raufu4Jessica Corron Chen5Department of Veterinary Public Health and Preventive Medicine, University of Ilorin, Ilorin, NigeriaDepartment of Veterinary Pathology, University of Ibadan, Ibadan, NigeriaDepartment of Virology, University of Ibadan, Ibadan, NigeriaViral Research Division, National Veterinary Research Institute, Vom, NigeriaDepartment of Veterinary Microbiology, University of Ilorin, NigeriaFood, Nutrition and Health Program, Faculty of Land and Food Systems, University of British Columbia, Vancouver, CanadaBackground: This study determined current status of laboratory biosafety in Nigerian veterinary research facilities. Methods: A questionnaire was developed to obtain information from researchers across Nigeria from July 2014 to July 2015. Information regarding demographics, knowledge of laboratory biosafety, availability and proper use of personal protective equipment (PPE), any priority pathogens researched, attitude on and use of standard laboratory practices, and biosafety awareness was obtained using a numeric scoring system. Data were analyzed with descriptive statistics, and univariate and multivariate logistic regression. Results: A total of 74 participants from 19 facilities completed the questionnaire. General knowledge scores ranged from 3 to 28 (out of 28 possible points), with 94.6% of respondents receiving low scores (scores < mean + 1 standard deviation). Very few (17.6%) reported availability or use PPE. Many participants (63.5%) reported no access to biosafety level (BSL)-1–3 facilities. None reported availability of a BSL-4 facility. Knowledge scores pertaining to biosafety management practices ranged from 0 to 14 (out of 14 possible points) with 47.3% of respondents receiving good scores (scores > mean + 1 standard deviation). Only 16.2% of respondents (from four facilities) reported having biosafety officers. Rabies virus was the most researched pathogen (31.1% of respondents). The majority (71.6%) were unaware of laws guiding biosafety. Researchers [odds ratio (OR) = 18.0; 95% confidence interval (CI): 1.63, 198.5; p = 0.023], especially in BSL-2 (OR = 258.5; 95% CI: 12.71, 5256; p < 0.001) facility of research institute (OR = 25.0; 95% CI: 5.18, 120.6; p < 0.001), are more likely to have adequate access to and properly utilize biosafety devices and PPE. Conclusions: Current knowledge of laboratory biosafety is limited except among a few researchers.http://www.sciencedirect.com/science/article/pii/S2093791116301275biosafetyfacilitiesNigeriaresearchveterinary |
| spellingShingle | Ismail Ayoade Odetokun Afusat Toyin Jagun-Jubril Bernard A. Onoja Yiltawe Simwal Wungak Ibrahim Adisa Raufu Jessica Corron Chen Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria Safety and Health at Work biosafety facilities Nigeria research veterinary |
| title | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
| title_full | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
| title_fullStr | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
| title_full_unstemmed | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
| title_short | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
| title_sort | status of laboratory biosafety and biosecurity in veterinary research facilities in nigeria |
| topic | biosafety facilities Nigeria research veterinary |
| url | http://www.sciencedirect.com/science/article/pii/S2093791116301275 |
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