Aspirin sensitizes osimertinib‐resistant NSCLC cells in vitro and in vivo via Bim‐dependent apoptosis induction

Aspirin sensitizes osimertinib‐resistant NSCLC cells in vitro and in vivo via Bim‐dependent apoptosis induction

Osimertinib, a third‐generation irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI), provides marked clinical benefit for patients with EGFR‐activating mutations. Unfortunately, limited treatments exist for patients who acquire osimertinib resistance. We observed two ‘...

Bibliográfalaš dieđut
Váldodahkkit:	Rui Han, Shuai Hao, Conghua Lu, Chong Zhang, Caiyu Lin, Li Li, Yubo Wang, Chen Hu, Yong He
Materiálatiipa:	Artihkal
Giella:	English
Almmustuhtton:	Wiley 2020-06-01
Ráidu:	Molecular Oncology
Fáttát:	apoptosis aspirin EGFR‐TKI osimertinib resistance
Liŋkkat:	https://doi.org/10.1002/1878-0261.12682

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