Body weight reduction by exercise increases the urinary 3-methylhistidine excretion level with relatively positive nitrogen, sodium, and potassium balances when compared to dietary restriction
Background: Regarding changes in muscle mass, differences due to types of exercise and/or nutritional interventions, and associations with nutrient balances are still unclear. Methods: To estimate changes in muscle mass during a body weight loss program using either a diet or exercise regimen, we in...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023068408 |
| _version_ | 1797669824951746560 |
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| author | Tetsuo Yamada Shin-ichi Kurasawa Masami Matsuzaki Akira Tanaka |
| author_facet | Tetsuo Yamada Shin-ichi Kurasawa Masami Matsuzaki Akira Tanaka |
| author_sort | Tetsuo Yamada |
| collection | DOAJ |
| description | Background: Regarding changes in muscle mass, differences due to types of exercise and/or nutritional interventions, and associations with nutrient balances are still unclear. Methods: To estimate changes in muscle mass during a body weight loss program using either a diet or exercise regimen, we investigated levels of muscle mass-related indices, and body contents of nitrogen, sodium, and potassium as measured by the balance method. Six healthy young adult male volunteers participated in two 10-day crossover experiments (20 days total). The first 5 days comprised an adjustment period (energy intake, 2656 ± 367 kcal/day (mean ± standard deviation)). During the second 5-day period, the participants either reduced their energy intake to 1770 ± 244 kcal/day (diet regimen) or exercised on a bicycle ergometer to expend 886 ± 122 kcal/day (exercise regimen). Results: The nitrogen, sodium, and potassium balances were significantly more positive during the exercise regimen than during the diet regimen. The urinary excretion levels of creatinine, 3-methylhistidine (3-MH), aldosterone, and catecholamines, and the 3-MH/creatinine ratio were significantly increased only during the exercise regimen. Conclusions: The exercise regimen suppresses the decrease in muscle mass-related indices during body weight loss compared to the diet regimen with a relatively positive state of whole-body protein, sodium, and potassium balances, accompanied by an increase in sympathetic/adrenal cortical functions. |
| first_indexed | 2024-03-11T20:50:24Z |
| format | Article |
| id | doaj.art-3072b666abd848b08efcd93991e6fa69 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-11T20:50:24Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-3072b666abd848b08efcd93991e6fa692023-10-01T06:00:35ZengElsevierHeliyon2405-84402023-09-0199e19632Body weight reduction by exercise increases the urinary 3-methylhistidine excretion level with relatively positive nitrogen, sodium, and potassium balances when compared to dietary restrictionTetsuo Yamada0Shin-ichi Kurasawa1Masami Matsuzaki2Akira Tanaka3Department of Nutrition and Dietetics, Kanto Gakuin University, Yokohama, Japan; Corresponding author. 1-50-1 Mutsuura-higashi, Kanazawa-ku, Yokohama, Kanagawa, 236-8503, Japan.Department of Nutrition and Dietetics, Kanto Gakuin University, Yokohama, Japan; Kanto Gakuin University, Yokohama, JapanDepartment of Nutrition and Dietetics, Kanto Gakuin University, Yokohama, Japan; Department of Nutritional Management, Hana Professional Training of College, Tokyo, JapanKagawa Nutrition University, Sakado, Japan; Kichijoji Futaba Professional and Vocational College of Culinary Nutrition, Tokyo, JapanBackground: Regarding changes in muscle mass, differences due to types of exercise and/or nutritional interventions, and associations with nutrient balances are still unclear. Methods: To estimate changes in muscle mass during a body weight loss program using either a diet or exercise regimen, we investigated levels of muscle mass-related indices, and body contents of nitrogen, sodium, and potassium as measured by the balance method. Six healthy young adult male volunteers participated in two 10-day crossover experiments (20 days total). The first 5 days comprised an adjustment period (energy intake, 2656 ± 367 kcal/day (mean ± standard deviation)). During the second 5-day period, the participants either reduced their energy intake to 1770 ± 244 kcal/day (diet regimen) or exercised on a bicycle ergometer to expend 886 ± 122 kcal/day (exercise regimen). Results: The nitrogen, sodium, and potassium balances were significantly more positive during the exercise regimen than during the diet regimen. The urinary excretion levels of creatinine, 3-methylhistidine (3-MH), aldosterone, and catecholamines, and the 3-MH/creatinine ratio were significantly increased only during the exercise regimen. Conclusions: The exercise regimen suppresses the decrease in muscle mass-related indices during body weight loss compared to the diet regimen with a relatively positive state of whole-body protein, sodium, and potassium balances, accompanied by an increase in sympathetic/adrenal cortical functions.http://www.sciencedirect.com/science/article/pii/S2405844023068408Body weight reductionExercise regimenDiet regimenCreatinine3-MethylhistidineBalance data |
| spellingShingle | Tetsuo Yamada Shin-ichi Kurasawa Masami Matsuzaki Akira Tanaka Body weight reduction by exercise increases the urinary 3-methylhistidine excretion level with relatively positive nitrogen, sodium, and potassium balances when compared to dietary restriction Heliyon Body weight reduction Exercise regimen Diet regimen Creatinine 3-Methylhistidine Balance data |
| title | Body weight reduction by exercise increases the urinary 3-methylhistidine excretion level with relatively positive nitrogen, sodium, and potassium balances when compared to dietary restriction |
| title_full | Body weight reduction by exercise increases the urinary 3-methylhistidine excretion level with relatively positive nitrogen, sodium, and potassium balances when compared to dietary restriction |
| title_fullStr | Body weight reduction by exercise increases the urinary 3-methylhistidine excretion level with relatively positive nitrogen, sodium, and potassium balances when compared to dietary restriction |
| title_full_unstemmed | Body weight reduction by exercise increases the urinary 3-methylhistidine excretion level with relatively positive nitrogen, sodium, and potassium balances when compared to dietary restriction |
| title_short | Body weight reduction by exercise increases the urinary 3-methylhistidine excretion level with relatively positive nitrogen, sodium, and potassium balances when compared to dietary restriction |
| title_sort | body weight reduction by exercise increases the urinary 3 methylhistidine excretion level with relatively positive nitrogen sodium and potassium balances when compared to dietary restriction |
| topic | Body weight reduction Exercise regimen Diet regimen Creatinine 3-Methylhistidine Balance data |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023068408 |
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