From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors
Abstract Field‐effect transistors have strong applications in biosensing field from pH and glucose monitoring to genomics, proteomics, cell signaling assays, and biomedical diagnostics in general. Notable advantages are the high sensitivity (thanks to intrinsic amplification), quick response (useful...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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Wiley-VCH
2023-12-01
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Series: | Electrochemical Science Advances |
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Online Access: | https://doi.org/10.1002/elsa.202200006 |
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author | Silvia Rizzato Anna Grazia Monteduro Angelo Leo Maria Teresa Todaro Giuseppe Maruccio |
author_facet | Silvia Rizzato Anna Grazia Monteduro Angelo Leo Maria Teresa Todaro Giuseppe Maruccio |
author_sort | Silvia Rizzato |
collection | DOAJ |
description | Abstract Field‐effect transistors have strong applications in biosensing field from pH and glucose monitoring to genomics, proteomics, cell signaling assays, and biomedical diagnostics in general. Notable advantages are the high sensitivity (thanks to intrinsic amplification), quick response (useful for real‐time monitoring), suitability for miniaturization, and compact portable read‐out systems. The initial concept of ion‐sensitive field‐effect transistors evolved with the emergence of novel classes of materials beyond traditional semiconductors. Recently, 2D nanomaterials are redesigning the field providing superior performances with large surface‐to‐volume ratio, high carrier mobility, more effective local gating, high transconductance, and operation at low voltages. Here, after a brief conceptual introduction, we review progresses and perspectives of 2D materials field‐effect‐transistor biosensors with special focus on opportunities, most recent applications, present challenges, and future perspectives. |
first_indexed | 2024-03-09T01:31:03Z |
format | Article |
id | doaj.art-307adb4c0289494199827fa7102f8c70 |
institution | Directory Open Access Journal |
issn | 2698-5977 |
language | English |
last_indexed | 2024-03-09T01:31:03Z |
publishDate | 2023-12-01 |
publisher | Wiley-VCH |
record_format | Article |
series | Electrochemical Science Advances |
spelling | doaj.art-307adb4c0289494199827fa7102f8c702023-12-09T12:10:57ZengWiley-VCHElectrochemical Science Advances2698-59772023-12-0136n/an/a10.1002/elsa.202200006From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensorsSilvia Rizzato0Anna Grazia Monteduro1Angelo Leo2Maria Teresa Todaro3Giuseppe Maruccio4Omnics Research Group, Department of Mathematics and Physics “Ennio De Giorgi” University of Salento and INFN Sezione di Lecce Lecce ItalyOmnics Research Group, Department of Mathematics and Physics “Ennio De Giorgi” University of Salento and INFN Sezione di Lecce Lecce ItalyOmnics Research Group, Department of Mathematics and Physics “Ennio De Giorgi” University of Salento and INFN Sezione di Lecce Lecce ItalyInstitute of Nanotechnology CNR‐Nanotec Lecce ItalyOmnics Research Group, Department of Mathematics and Physics “Ennio De Giorgi” University of Salento and INFN Sezione di Lecce Lecce ItalyAbstract Field‐effect transistors have strong applications in biosensing field from pH and glucose monitoring to genomics, proteomics, cell signaling assays, and biomedical diagnostics in general. Notable advantages are the high sensitivity (thanks to intrinsic amplification), quick response (useful for real‐time monitoring), suitability for miniaturization, and compact portable read‐out systems. The initial concept of ion‐sensitive field‐effect transistors evolved with the emergence of novel classes of materials beyond traditional semiconductors. Recently, 2D nanomaterials are redesigning the field providing superior performances with large surface‐to‐volume ratio, high carrier mobility, more effective local gating, high transconductance, and operation at low voltages. Here, after a brief conceptual introduction, we review progresses and perspectives of 2D materials field‐effect‐transistor biosensors with special focus on opportunities, most recent applications, present challenges, and future perspectives.https://doi.org/10.1002/elsa.202200006biosensingfield‐effect‐transistorgrapheneISFETtransition metal dichalcogenidestwo‐dimensional nanomaterials |
spellingShingle | Silvia Rizzato Anna Grazia Monteduro Angelo Leo Maria Teresa Todaro Giuseppe Maruccio From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors Electrochemical Science Advances biosensing field‐effect‐transistor graphene ISFET transition metal dichalcogenides two‐dimensional nanomaterials |
title | From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors |
title_full | From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors |
title_fullStr | From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors |
title_full_unstemmed | From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors |
title_short | From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors |
title_sort | from ion sensitive field effect transistor to 2d materials field effect transistor biosensors |
topic | biosensing field‐effect‐transistor graphene ISFET transition metal dichalcogenides two‐dimensional nanomaterials |
url | https://doi.org/10.1002/elsa.202200006 |
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