From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors

Abstract Field‐effect transistors have strong applications in biosensing field from pH and glucose monitoring to genomics, proteomics, cell signaling assays, and biomedical diagnostics in general. Notable advantages are the high sensitivity (thanks to intrinsic amplification), quick response (useful...

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Main Authors: Silvia Rizzato, Anna Grazia Monteduro, Angelo Leo, Maria Teresa Todaro, Giuseppe Maruccio
Format: Article
Language:English
Published: Wiley-VCH 2023-12-01
Series:Electrochemical Science Advances
Subjects:
Online Access:https://doi.org/10.1002/elsa.202200006
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author Silvia Rizzato
Anna Grazia Monteduro
Angelo Leo
Maria Teresa Todaro
Giuseppe Maruccio
author_facet Silvia Rizzato
Anna Grazia Monteduro
Angelo Leo
Maria Teresa Todaro
Giuseppe Maruccio
author_sort Silvia Rizzato
collection DOAJ
description Abstract Field‐effect transistors have strong applications in biosensing field from pH and glucose monitoring to genomics, proteomics, cell signaling assays, and biomedical diagnostics in general. Notable advantages are the high sensitivity (thanks to intrinsic amplification), quick response (useful for real‐time monitoring), suitability for miniaturization, and compact portable read‐out systems. The initial concept of ion‐sensitive field‐effect transistors evolved with the emergence of novel classes of materials beyond traditional semiconductors. Recently, 2D nanomaterials are redesigning the field providing superior performances with large surface‐to‐volume ratio, high carrier mobility, more effective local gating, high transconductance, and operation at low voltages. Here, after a brief conceptual introduction, we review progresses and perspectives of 2D materials field‐effect‐transistor biosensors with special focus on opportunities, most recent applications, present challenges, and future perspectives.
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spelling doaj.art-307adb4c0289494199827fa7102f8c702023-12-09T12:10:57ZengWiley-VCHElectrochemical Science Advances2698-59772023-12-0136n/an/a10.1002/elsa.202200006From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensorsSilvia Rizzato0Anna Grazia Monteduro1Angelo Leo2Maria Teresa Todaro3Giuseppe Maruccio4Omnics Research Group, Department of Mathematics and Physics “Ennio De Giorgi” University of Salento and INFN Sezione di Lecce Lecce ItalyOmnics Research Group, Department of Mathematics and Physics “Ennio De Giorgi” University of Salento and INFN Sezione di Lecce Lecce ItalyOmnics Research Group, Department of Mathematics and Physics “Ennio De Giorgi” University of Salento and INFN Sezione di Lecce Lecce ItalyInstitute of Nanotechnology CNR‐Nanotec Lecce ItalyOmnics Research Group, Department of Mathematics and Physics “Ennio De Giorgi” University of Salento and INFN Sezione di Lecce Lecce ItalyAbstract Field‐effect transistors have strong applications in biosensing field from pH and glucose monitoring to genomics, proteomics, cell signaling assays, and biomedical diagnostics in general. Notable advantages are the high sensitivity (thanks to intrinsic amplification), quick response (useful for real‐time monitoring), suitability for miniaturization, and compact portable read‐out systems. The initial concept of ion‐sensitive field‐effect transistors evolved with the emergence of novel classes of materials beyond traditional semiconductors. Recently, 2D nanomaterials are redesigning the field providing superior performances with large surface‐to‐volume ratio, high carrier mobility, more effective local gating, high transconductance, and operation at low voltages. Here, after a brief conceptual introduction, we review progresses and perspectives of 2D materials field‐effect‐transistor biosensors with special focus on opportunities, most recent applications, present challenges, and future perspectives.https://doi.org/10.1002/elsa.202200006biosensingfield‐effect‐transistorgrapheneISFETtransition metal dichalcogenidestwo‐dimensional nanomaterials
spellingShingle Silvia Rizzato
Anna Grazia Monteduro
Angelo Leo
Maria Teresa Todaro
Giuseppe Maruccio
From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors
Electrochemical Science Advances
biosensing
field‐effect‐transistor
graphene
ISFET
transition metal dichalcogenides
two‐dimensional nanomaterials
title From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors
title_full From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors
title_fullStr From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors
title_full_unstemmed From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors
title_short From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors
title_sort from ion sensitive field effect transistor to 2d materials field effect transistor biosensors
topic biosensing
field‐effect‐transistor
graphene
ISFET
transition metal dichalcogenides
two‐dimensional nanomaterials
url https://doi.org/10.1002/elsa.202200006
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