Computer Analysis of the Inhibition of ACE2 by Flavonoids and Identification of Their Potential Antiviral Pharmacophore Site

Computer Analysis of the Inhibition of ACE2 by Flavonoids and Identification of Their Potential Antiviral Pharmacophore Site

In the present study, we investigated the antiviral activities of 17 flavonoids as natural products. These derivatives were evaluated for their in vitro antiviral activities against HIV and SARS-CoV-2. Their antiviral activity was evaluated for the first time based on POM (Petra/Osiris/Molispiration...

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Bibliographic Details
Main Authors: Andrey Bogoyavlenskiy, Madina Alexyuk, Pavel Alexyuk, Vladimir Berezin, Faisal A. Almalki, Taibi Ben Hadda, Alaa M. Alqahtani, Saleh A. Ahmed, Stefano Dall’Acqua, Joazaizulfazli Jamalis
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
plant compounds
flavonoids
inhibition of the ACE2 protein
docking
POM (Petra/Osiris/Molinspiration) analyses
Online Access:https://www.mdpi.com/1420-3049/28/9/3766

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