Intranasal Administration of Nanovectorized Docosahexaenoic Acid (DHA) Improves Cognitive Function in Two Complementary Mouse Models of Alzheimer’s Disease

Intranasal Administration of Nanovectorized Docosahexaenoic Acid (DHA) Improves Cognitive Function in Two Complementary Mouse Models of Alzheimer’s Disease

Polyunsaturated fatty acids (PUFAs) are a class of fatty acids that are closely associated with the development and function of the brain. The most abundant PUFA is docosahexaenoic acid (DHA, 22:6 <i>n</i>-3). In humans, low plasmatic concentrations of DHA have been associated with impai...

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Bibliographic Details
Main Authors: Charleine Zussy, Rijo John, Théo Urgin, Léa Otaegui, Claire Vigor, Niyazi Acar, Geoffrey Canet, Mathieu Vitalis, Françoise Morin, Emmanuel Planel, Camille Oger, Thierry Durand, Shinde L. Rajshree, Laurent Givalois, Padma V. Devarajan, Catherine Desrumaux
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Antioxidants
Subjects:
omega-3 fatty acids
docosahexaenoic acid
curcumin
Alzheimer’s disease
amyloid-β peptide
intranasal
Online Access:https://www.mdpi.com/2076-3921/11/5/838

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