Sportmedizin im Wandel
Problem: Dyslipidaemia and physical inactivity are leading risk factors for the development of atherosclerotic disease, accounting annually for approximately 5.8 million deaths worldwide. A lipid-lowering effect of exercise is commonly assumed, but, in contrast to multi-modal lifestyle interventions...
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| Format: | Article |
| Language: | deu |
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Dynamic Media Sales Verlag
2017-11-01
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| Series: | Deutsche Zeitschrift für Sportmedizin |
| Online Access: | https://www.germanjournalsportsmedicine.com/archive/archive-2017/heft-11/a-run-a-day-keeps-lipids-at-bay-regular-exercise-as-a-treatment-of-dyslipidaemias/ |
| Summary: | Problem: Dyslipidaemia and physical inactivity are leading risk factors for the development of atherosclerotic disease, accounting annually for approximately 5.8 million deaths worldwide. A lipid-lowering effect of exercise is commonly assumed, but, in contrast to multi-modal lifestyle interventions, the particular effect of exercise on lipid profiles is less-wellestablished. Methods: Systematic literature search for epidemiological and randomized trials, reviews and meta-analyses evaluating the particular effects of high fitness or exercise interventions on changes in lipid levels. Results: A higher fitness assessed by exercise testing is moderately associated with favourable HDL-cholesterol and triglyceride, but not LDL levels. This is confirmed by findings from randomized trials and meta-analyses, but effects are not consistently observed. Moderate aerobic exercise is preferred over resistance or high-intensity interval exercise. Besides absolute lipid values, exercise favourably influences atherogenic lipid subfractions. The combination of statins with exercise improves clinical outcomes; thus, statins should not be withheld if indicated according to guidelines.Discussion: The effect of exercise on lipid levels is at best moderate, with small improvements in HDL and triglyceride, but not LDL levels. Nonetheless, dyslipidaemia is rarely observed as a single risk factor, and exercise remains a cornerstone of multimodal lifestyle interventions to favourably modify cardiovascular risk.KEY WORDS: Fitness, Exercise, Dyslipidaemia, LDL, Statins |
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| ISSN: | 0344-5925 2510-5264 |