Sportmedizin im Wandel

Problem: Dyslipidaemia and physical inactivity are leading risk factors for the development of atherosclerotic disease, accounting annually for approximately 5.8 million deaths worldwide. A lipid-lowering effect of exercise is commonly assumed, but, in contrast to multi-modal lifestyle interventions...

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Main Author: Pressler A
Format: Article
Language:deu
Published: Dynamic Media Sales Verlag 2017-11-01
Series:Deutsche Zeitschrift für Sportmedizin
Online Access:https://www.germanjournalsportsmedicine.com/archive/archive-2017/heft-11/a-run-a-day-keeps-lipids-at-bay-regular-exercise-as-a-treatment-of-dyslipidaemias/
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author Pressler A
author_facet Pressler A
author_sort Pressler A
collection DOAJ
description Problem: Dyslipidaemia and physical inactivity are leading risk factors for the development of atherosclerotic disease, accounting annually for approximately 5.8 million deaths worldwide. A lipid-lowering effect of exercise is commonly assumed, but, in contrast to multi-modal lifestyle interventions, the particular effect of exercise on lipid profiles is less-wellestablished. Methods: Systematic literature search for epidemiological and randomized trials, reviews and meta-analyses evaluating the particular effects of high fitness or exercise interventions on changes in lipid levels. Results: A higher fitness assessed by exercise testing is moderately associated with favourable HDL-cholesterol and triglyceride, but not LDL levels. This is confirmed by findings from randomized trials and meta-analyses, but effects are not consistently observed. Moderate aerobic exercise is preferred over resistance or high-intensity interval exercise. Besides absolute lipid values, exercise favourably influences atherogenic lipid subfractions. The combination of statins with exercise improves clinical outcomes; thus, statins should not be withheld if indicated according to guidelines.Discussion: The effect of exercise on lipid levels is at best moderate, with small improvements in HDL and triglyceride, but not LDL levels. Nonetheless, dyslipidaemia is rarely observed as a single risk factor, and exercise remains a cornerstone of multimodal lifestyle interventions to favourably modify cardiovascular risk.KEY WORDS: Fitness, Exercise, Dyslipidaemia, LDL, Statins
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spelling doaj.art-308553696cda4ae09b1a1e142dc7ade52023-07-04T17:04:30ZdeuDynamic Media Sales VerlagDeutsche Zeitschrift für Sportmedizin0344-59252510-52642017-11-01681110.5960/dzsm.2017.304304635Sportmedizin im WandelPressler AProblem: Dyslipidaemia and physical inactivity are leading risk factors for the development of atherosclerotic disease, accounting annually for approximately 5.8 million deaths worldwide. A lipid-lowering effect of exercise is commonly assumed, but, in contrast to multi-modal lifestyle interventions, the particular effect of exercise on lipid profiles is less-wellestablished. Methods: Systematic literature search for epidemiological and randomized trials, reviews and meta-analyses evaluating the particular effects of high fitness or exercise interventions on changes in lipid levels. Results: A higher fitness assessed by exercise testing is moderately associated with favourable HDL-cholesterol and triglyceride, but not LDL levels. This is confirmed by findings from randomized trials and meta-analyses, but effects are not consistently observed. Moderate aerobic exercise is preferred over resistance or high-intensity interval exercise. Besides absolute lipid values, exercise favourably influences atherogenic lipid subfractions. The combination of statins with exercise improves clinical outcomes; thus, statins should not be withheld if indicated according to guidelines.Discussion: The effect of exercise on lipid levels is at best moderate, with small improvements in HDL and triglyceride, but not LDL levels. Nonetheless, dyslipidaemia is rarely observed as a single risk factor, and exercise remains a cornerstone of multimodal lifestyle interventions to favourably modify cardiovascular risk.KEY WORDS: Fitness, Exercise, Dyslipidaemia, LDL, Statinshttps://www.germanjournalsportsmedicine.com/archive/archive-2017/heft-11/a-run-a-day-keeps-lipids-at-bay-regular-exercise-as-a-treatment-of-dyslipidaemias/
spellingShingle Pressler A
Sportmedizin im Wandel
Deutsche Zeitschrift für Sportmedizin
title Sportmedizin im Wandel
title_full Sportmedizin im Wandel
title_fullStr Sportmedizin im Wandel
title_full_unstemmed Sportmedizin im Wandel
title_short Sportmedizin im Wandel
title_sort sportmedizin im wandel
url https://www.germanjournalsportsmedicine.com/archive/archive-2017/heft-11/a-run-a-day-keeps-lipids-at-bay-regular-exercise-as-a-treatment-of-dyslipidaemias/
work_keys_str_mv AT presslera sportmedizinimwandel