Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomography
Purpose: To establish normative data on anterior scleral thickness using the spectral domain anterior segment optical coherence tomography (AS-OCT). Methods: In total, 200 eyes of 100 healthy subjects underwent AS-OCT scans in the temporal and nasal quadrants. The scleral + conjunctival complex th...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=5;spage=1833;epage=1836;aulast=Kommula |
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| author | Hasna Kommula Somasheila I Murthy Abhinav Loomba Ashik Mohamed Rashmi Ranjan |
| author_facet | Hasna Kommula Somasheila I Murthy Abhinav Loomba Ashik Mohamed Rashmi Ranjan |
| author_sort | Hasna Kommula |
| collection | DOAJ |
| description | Purpose: To establish normative data on anterior scleral thickness using the spectral domain anterior segment optical coherence tomography (AS-OCT). Methods: In total, 200 eyes of 100 healthy subjects underwent AS-OCT scans in the temporal and nasal quadrants. The scleral + conjunctival complex thickness (SCT) was measured by a single examiner. Mean SCT was analyzed for differences across age groups, gender, and location (nasal versus temporal). Results: Mean age was 46.4 ± 18.3 (21–84) years; male to female ratio was 54:46. Mean SCT (nasal + temporal) of the right eye (RE) was 682.3 ± 64.2 μm in males and 660.6 ± 57.1 μm in females. In the left eye (LE), it was 684.6 ± 64.9 μm in males and 661.8 ± 49.3 μm in females. These differences between male and female for both eyes were statistically significant (P = 0.006 and P = 0.002). The mean SCT of temporal and nasal quadrants in the RE was 678.54 ± 57.50 and 666 ± 66.2 μm, respectively. In the LE, the temporal mean SCT quadrant was 679.6 ± 55.8 μm, and the nasal was 668.6 ± 63.6 μm. Age had a negative correlation with SCT (−0.62 μm/year; P = 0.03), and males had a higher temporal SCT than females (22 μm higher; P = 0.03). After adjusting for age and gender in a multivariate analysis, temporal SCT was significantly (P < 0.001) higher than nasal SCT. Conclusion: In our study, mean SCT decreased with age and males had a higher temporal SCT. This is the first study to evaluate scleral thickness in the Indian population, and the data can be used as a baseline for comparing variations in scleral thickness in disease. |
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| format | Article |
| id | doaj.art-30857292dc4642d79c3c1a827921a9d3 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-03-12T22:31:26Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-30857292dc4642d79c3c1a827921a9d32023-07-21T15:14:09ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892023-01-017151833183610.4103/ijo.IJO_2046_22Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomographyHasna KommulaSomasheila I MurthyAbhinav LoombaAshik MohamedRashmi RanjanPurpose: To establish normative data on anterior scleral thickness using the spectral domain anterior segment optical coherence tomography (AS-OCT). Methods: In total, 200 eyes of 100 healthy subjects underwent AS-OCT scans in the temporal and nasal quadrants. The scleral + conjunctival complex thickness (SCT) was measured by a single examiner. Mean SCT was analyzed for differences across age groups, gender, and location (nasal versus temporal). Results: Mean age was 46.4 ± 18.3 (21–84) years; male to female ratio was 54:46. Mean SCT (nasal + temporal) of the right eye (RE) was 682.3 ± 64.2 μm in males and 660.6 ± 57.1 μm in females. In the left eye (LE), it was 684.6 ± 64.9 μm in males and 661.8 ± 49.3 μm in females. These differences between male and female for both eyes were statistically significant (P = 0.006 and P = 0.002). The mean SCT of temporal and nasal quadrants in the RE was 678.54 ± 57.50 and 666 ± 66.2 μm, respectively. In the LE, the temporal mean SCT quadrant was 679.6 ± 55.8 μm, and the nasal was 668.6 ± 63.6 μm. Age had a negative correlation with SCT (−0.62 μm/year; P = 0.03), and males had a higher temporal SCT than females (22 μm higher; P = 0.03). After adjusting for age and gender in a multivariate analysis, temporal SCT was significantly (P < 0.001) higher than nasal SCT. Conclusion: In our study, mean SCT decreased with age and males had a higher temporal SCT. This is the first study to evaluate scleral thickness in the Indian population, and the data can be used as a baseline for comparing variations in scleral thickness in disease.http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=5;spage=1833;epage=1836;aulast=Kommulaanterior segment octnormative datascleral thicknessspectral domain |
| spellingShingle | Hasna Kommula Somasheila I Murthy Abhinav Loomba Ashik Mohamed Rashmi Ranjan Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomography Indian Journal of Ophthalmology anterior segment oct normative data scleral thickness spectral domain |
| title | Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomography |
| title_full | Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomography |
| title_fullStr | Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomography |
| title_full_unstemmed | Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomography |
| title_short | Scleral thickness in normal Indian eyes measured using spectral domain anterior segment optical coherence tomography |
| title_sort | scleral thickness in normal indian eyes measured using spectral domain anterior segment optical coherence tomography |
| topic | anterior segment oct normative data scleral thickness spectral domain |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=5;spage=1833;epage=1836;aulast=Kommula |
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