Liquiritin Attenuates Pathological Cardiac Hypertrophy by Activating the PKA/LKB1/AMPK Pathway

Liquiritin Attenuates Pathological Cardiac Hypertrophy by Activating the PKA/LKB1/AMPK Pathway

Background: Liquiritin (LQ) is one of the main flavonoids extracted from the roots of Glycyrrhiza spp., which are widely used in traditional Chinese medicine. Studies in both cellular and animal disease models have shown that LQ attenuates or prevents oxidative stress, inflammation, and apoptosis. H...

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Bibliographic Details
Main Authors: Xiahenazi Aiyasiding, Hai-Han Liao, Hong Feng, Nan Zhang, Zheng Lin, Wen Ding, Han Yan, Zi-Ying Zhou, Qi-Zhu Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
liquiritin
cardiac hypertrophy
heart
AMPKα2
PKA
cAMP
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.870699/full

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