SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia

SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia

BackgroundOxidative stress and impaired autophagic flux play important roles in the development of peripheral artery disease (PAD). SS31 is considered an important antioxidant peptide and autophagy regulator. We aimed to investigate the role of SS31 in PAD myopathy and its possible mechanism both in...

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Bibliographic Details
Main Authors: Qiaoyun Yang, Chunqiu Li, Qingwei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
peripheral artery disease (PAD)
Szeto-Schiller peptide
autophagic flux
oxidative stress
AKT-mTOR pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.789331/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.789331/full

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