Therapeutic Applications of Antimicrobial Silver-Based Biomaterials in Dentistry
Qiyu Wang,1,* Yu Zhang,1,* Qiang Li,2,* Li Chen,1 Hui Liu,1 Meng Ding,2 Heng Dong,1 Yongbin Mou1 1Department of Oral Implantology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, People’s Republic of China; 2Central Laboratory, Nanjing Stomatological Hospita...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-01-01
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| Series: | International Journal of Nanomedicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/therapeutic-applications-of-antimicrobial-silver-based-biomaterials-in-peer-reviewed-fulltext-article-IJN |
| _version_ | 1819288976072114176 |
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| author | Wang Q Zhang Y Li Q Chen L Liu H Ding M Dong H Mou Y |
| author_facet | Wang Q Zhang Y Li Q Chen L Liu H Ding M Dong H Mou Y |
| author_sort | Wang Q |
| collection | DOAJ |
| description | Qiyu Wang,1,* Yu Zhang,1,* Qiang Li,2,* Li Chen,1 Hui Liu,1 Meng Ding,2 Heng Dong,1 Yongbin Mou1 1Department of Oral Implantology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, People’s Republic of China; 2Central Laboratory, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yongbin Mou; Heng DongDepartment of Oral Implantology, Nanjing Stomatological Hospital, Medical School of Nanjing University, #30 Zhongyang Road, Nanjing, 210008, People’s Republic of China, Tel +86 25 83620236, Fax +86 25 83620202, Email yongbinmou@163.com; dongheng90@smail.nju.edu.cnAbstract: Microbial infection accounts for many dental diseases and treatment failure. Therefore, the antibacterial properties of dental biomaterials are of great importance to the long-term results of treatment. Silver-based biomaterials (AgBMs) have been widely researched as antimicrobial materials with high efficiency and relatively low toxicity. AgBMs have a broad spectrum of antimicrobial properties, including penetration of microbial cell membranes, damage to genetic material, contact killing, and dysfunction of bacterial proteins and enzymes. In particular, advances in nanotechnology have improved the application value of AgBMs. Hence, in many subspecialties of dentistry, AgBMs have been researched and employed, such as caries arresting or prevention, root canal sterilization, periodontal plaque inhibition, additives in dentures, coating of implants and anti-inflammatory material in oral and maxillofacial surgery. This paper aims to provide an overview of the application approaches of AgBMs in dentistry and present better guidance for oral antimicrobial therapy via the development of AgBMs.Keywords: silver, antimicrobial, dentistry, oral biofilm formation, biomaterials, nanotechnology |
| first_indexed | 2024-12-24T02:59:30Z |
| format | Article |
| id | doaj.art-308702b3fd6a40c4a835138cf930e58e |
| institution | Directory Open Access Journal |
| issn | 1178-2013 |
| language | English |
| last_indexed | 2024-12-24T02:59:30Z |
| publishDate | 2022-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Nanomedicine |
| spelling | doaj.art-308702b3fd6a40c4a835138cf930e58e2022-12-21T17:18:15ZengDove Medical PressInternational Journal of Nanomedicine1178-20132022-01-01Volume 1744346272561Therapeutic Applications of Antimicrobial Silver-Based Biomaterials in DentistryWang QZhang YLi QChen LLiu HDing MDong HMou YQiyu Wang,1,* Yu Zhang,1,* Qiang Li,2,* Li Chen,1 Hui Liu,1 Meng Ding,2 Heng Dong,1 Yongbin Mou1 1Department of Oral Implantology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, People’s Republic of China; 2Central Laboratory, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yongbin Mou; Heng DongDepartment of Oral Implantology, Nanjing Stomatological Hospital, Medical School of Nanjing University, #30 Zhongyang Road, Nanjing, 210008, People’s Republic of China, Tel +86 25 83620236, Fax +86 25 83620202, Email yongbinmou@163.com; dongheng90@smail.nju.edu.cnAbstract: Microbial infection accounts for many dental diseases and treatment failure. Therefore, the antibacterial properties of dental biomaterials are of great importance to the long-term results of treatment. Silver-based biomaterials (AgBMs) have been widely researched as antimicrobial materials with high efficiency and relatively low toxicity. AgBMs have a broad spectrum of antimicrobial properties, including penetration of microbial cell membranes, damage to genetic material, contact killing, and dysfunction of bacterial proteins and enzymes. In particular, advances in nanotechnology have improved the application value of AgBMs. Hence, in many subspecialties of dentistry, AgBMs have been researched and employed, such as caries arresting or prevention, root canal sterilization, periodontal plaque inhibition, additives in dentures, coating of implants and anti-inflammatory material in oral and maxillofacial surgery. This paper aims to provide an overview of the application approaches of AgBMs in dentistry and present better guidance for oral antimicrobial therapy via the development of AgBMs.Keywords: silver, antimicrobial, dentistry, oral biofilm formation, biomaterials, nanotechnologyhttps://www.dovepress.com/therapeutic-applications-of-antimicrobial-silver-based-biomaterials-in-peer-reviewed-fulltext-article-IJNsilverantimicrobialdentistryoral biofilm formationbiomaterialsnanotechnology |
| spellingShingle | Wang Q Zhang Y Li Q Chen L Liu H Ding M Dong H Mou Y Therapeutic Applications of Antimicrobial Silver-Based Biomaterials in Dentistry International Journal of Nanomedicine silver antimicrobial dentistry oral biofilm formation biomaterials nanotechnology |
| title | Therapeutic Applications of Antimicrobial Silver-Based Biomaterials in Dentistry |
| title_full | Therapeutic Applications of Antimicrobial Silver-Based Biomaterials in Dentistry |
| title_fullStr | Therapeutic Applications of Antimicrobial Silver-Based Biomaterials in Dentistry |
| title_full_unstemmed | Therapeutic Applications of Antimicrobial Silver-Based Biomaterials in Dentistry |
| title_short | Therapeutic Applications of Antimicrobial Silver-Based Biomaterials in Dentistry |
| title_sort | therapeutic applications of antimicrobial silver based biomaterials in dentistry |
| topic | silver antimicrobial dentistry oral biofilm formation biomaterials nanotechnology |
| url | https://www.dovepress.com/therapeutic-applications-of-antimicrobial-silver-based-biomaterials-in-peer-reviewed-fulltext-article-IJN |
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