Longitudinally Extensive Transverse Myelitis Associated with Cytomegalovirus Infection in an Immunocompetent Patient
Longitudinally extensive transverse myelitis (LETM) associated with cytomegalovirus infection is extremely rare and is, mainly observed in immunocompetent people. A 55-year-old woman with no evidence of immunosuppression was admitted with paresthesia in the lower limbs for 15 days, difficulty walkin...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
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| Series: | Microbiology Research |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2036-7481/13/3/36 |
| _version_ | 1827658790548275200 |
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| author | Raul Montalvo María-Fernanda Sánchez Vidal |
| author_facet | Raul Montalvo María-Fernanda Sánchez Vidal |
| author_sort | Raul Montalvo |
| collection | DOAJ |
| description | Longitudinally extensive transverse myelitis (LETM) associated with cytomegalovirus infection is extremely rare and is, mainly observed in immunocompetent people. A 55-year-old woman with no evidence of immunosuppression was admitted with paresthesia in the lower limbs for 15 days, difficulty walking, fecal incontinence, and acute urinary retention. Magnetic resonance imaging (MRI) in the T2 sequence showed signs of hyperintensity in the cervical and thoracic cord. The serological study showed IgM antibodies to cytomegalovirus, and the result of the FilmArray meningitis/encephalitis panel showed the presence of cytomegalovirus. She received treatment with methylprednisolone and ganciclovir with a favorable outcome. This case highlights the importance of investigating treatable causes in patients with longitudinally extensive transverse myelitis with acute presentation. |
| first_indexed | 2024-03-09T23:08:38Z |
| format | Article |
| id | doaj.art-3087466087d44138bdb2b4cc9eb4df09 |
| institution | Directory Open Access Journal |
| issn | 2036-7481 |
| language | English |
| last_indexed | 2024-03-09T23:08:38Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microbiology Research |
| spelling | doaj.art-3087466087d44138bdb2b4cc9eb4df092023-11-23T17:48:07ZengMDPI AGMicrobiology Research2036-74812022-08-0113352352910.3390/microbiolres13030036Longitudinally Extensive Transverse Myelitis Associated with Cytomegalovirus Infection in an Immunocompetent PatientRaul Montalvo0María-Fernanda Sánchez Vidal1Infectology Department, Universidad Cesar Vallejo, Trujillo 13001, PeruDepartamento Neuroinfectología, Instituto Nacional de Neurología y Neurocirugía, Mexico City 14269, MexicoLongitudinally extensive transverse myelitis (LETM) associated with cytomegalovirus infection is extremely rare and is, mainly observed in immunocompetent people. A 55-year-old woman with no evidence of immunosuppression was admitted with paresthesia in the lower limbs for 15 days, difficulty walking, fecal incontinence, and acute urinary retention. Magnetic resonance imaging (MRI) in the T2 sequence showed signs of hyperintensity in the cervical and thoracic cord. The serological study showed IgM antibodies to cytomegalovirus, and the result of the FilmArray meningitis/encephalitis panel showed the presence of cytomegalovirus. She received treatment with methylprednisolone and ganciclovir with a favorable outcome. This case highlights the importance of investigating treatable causes in patients with longitudinally extensive transverse myelitis with acute presentation.https://www.mdpi.com/2036-7481/13/3/36transverse myelitiscytomegalovirusimmunocompetentinfection |
| spellingShingle | Raul Montalvo María-Fernanda Sánchez Vidal Longitudinally Extensive Transverse Myelitis Associated with Cytomegalovirus Infection in an Immunocompetent Patient Microbiology Research transverse myelitis cytomegalovirus immunocompetent infection |
| title | Longitudinally Extensive Transverse Myelitis Associated with Cytomegalovirus Infection in an Immunocompetent Patient |
| title_full | Longitudinally Extensive Transverse Myelitis Associated with Cytomegalovirus Infection in an Immunocompetent Patient |
| title_fullStr | Longitudinally Extensive Transverse Myelitis Associated with Cytomegalovirus Infection in an Immunocompetent Patient |
| title_full_unstemmed | Longitudinally Extensive Transverse Myelitis Associated with Cytomegalovirus Infection in an Immunocompetent Patient |
| title_short | Longitudinally Extensive Transverse Myelitis Associated with Cytomegalovirus Infection in an Immunocompetent Patient |
| title_sort | longitudinally extensive transverse myelitis associated with cytomegalovirus infection in an immunocompetent patient |
| topic | transverse myelitis cytomegalovirus immunocompetent infection |
| url | https://www.mdpi.com/2036-7481/13/3/36 |
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