Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling

Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling

FoxL1<sup>+</sup>-Telocytes (TC<sup>FoxL1+</sup>) are subepithelial cells that form a network underneath the epithelium. We have shown that without inflammatory stress, mice with loss of function in the BMP signalling pathway in TC<sup>FoxL1+</sup> (<i>BmpR1...

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Bibliographic Details
Main Authors: Vilcy Reyes Nicolás, Joannie M. Allaire, Alain B. Alfonso, Dianne Pupo Gómez, Véronique Pomerleau, Véronique Giroux, François Boudreau, Nathalie Perreault
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
inflammatory bowel diseases
cellular microenvironment
wound healing
goblet cells
<i>O</i>-glycosylation
Online Access:https://www.mdpi.com/2073-4409/10/11/2954

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