Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city
The rapid spread of Metallo-b-lactamase (MBL) producing Gram negative bacilli represents a matter of great concern worldwide. The study analyzed the occurrence of MBL production in carbapenem resistant Pseudomonas and Acinetobacter isolates over one year period. A total of 132 Pseudomonas and 76 Aci...
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| Format: | Article |
| Language: | English |
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Ibrahim Medical College
2010-07-01
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| Series: | IMC Journal of Medical Science |
| Online Access: | http://www.imcjms.com/registration/journal_full_text/193 |
| _version_ | 1818669777863835648 |
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| author | Shaheda Anwar Md. Ruhul Amin Miah Ahmed Abu Saleh Humayun Sattar Sharmeen Ahmed |
| author_facet | Shaheda Anwar Md. Ruhul Amin Miah Ahmed Abu Saleh Humayun Sattar Sharmeen Ahmed |
| author_sort | Shaheda Anwar |
| collection | DOAJ |
| description | The rapid spread of Metallo-b-lactamase (MBL) producing Gram negative bacilli represents a matter of great concern worldwide. The study analyzed the occurrence of MBL production in carbapenem resistant Pseudomonas and Acinetobacter isolates over one year period. A total of 132 Pseudomonas and 76 Acinetobacter isolates were obtained from two tertiary care hospitals of Dhaka city. A total of 53 Pseudomonas and 29 Acinetobacter isolates were selected because of their resistance to carbapenem specially imipenem (IPM). Screening for MBL production was performed in these isolates by IPM-EDTA microdilution MIC method. 44 (83%) IPM resistant Pseudomonas and 19 (65.5%) Acinetobacter isolates were MBL producer by IPM-EDTA microdilution MIC method. These results suggest that MBL producing Pseudomonas and Acinetobacter isolates are emerging in our country and it is essential to screen carbapenem resistant isolates for MBL production.
Ibrahim Med. Coll. J. 2010; 4(2): 63-65 |
| first_indexed | 2024-12-17T06:57:37Z |
| format | Article |
| id | doaj.art-308c65717c5d47158438e866bfb673ef |
| institution | Directory Open Access Journal |
| issn | 2519-1721 2519-1586 |
| language | English |
| last_indexed | 2024-12-17T06:57:37Z |
| publishDate | 2010-07-01 |
| publisher | Ibrahim Medical College |
| record_format | Article |
| series | IMC Journal of Medical Science |
| spelling | doaj.art-308c65717c5d47158438e866bfb673ef2022-12-21T21:59:22ZengIbrahim Medical CollegeIMC Journal of Medical Science2519-17212519-15862010-07-01426365Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka cityShaheda Anwar0Md. Ruhul Amin Miah1Ahmed Abu Saleh2Humayun Sattar3Sharmeen Ahmed4Department of Microbiology, Ibrahim Medical College, Shahbag, Dhaka, BangladeshDepartment of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, BangladeshDepartment of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, BangladeshDepartment of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, BangladeshDepartment of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, BangladeshThe rapid spread of Metallo-b-lactamase (MBL) producing Gram negative bacilli represents a matter of great concern worldwide. The study analyzed the occurrence of MBL production in carbapenem resistant Pseudomonas and Acinetobacter isolates over one year period. A total of 132 Pseudomonas and 76 Acinetobacter isolates were obtained from two tertiary care hospitals of Dhaka city. A total of 53 Pseudomonas and 29 Acinetobacter isolates were selected because of their resistance to carbapenem specially imipenem (IPM). Screening for MBL production was performed in these isolates by IPM-EDTA microdilution MIC method. 44 (83%) IPM resistant Pseudomonas and 19 (65.5%) Acinetobacter isolates were MBL producer by IPM-EDTA microdilution MIC method. These results suggest that MBL producing Pseudomonas and Acinetobacter isolates are emerging in our country and it is essential to screen carbapenem resistant isolates for MBL production. Ibrahim Med. Coll. J. 2010; 4(2): 63-65http://www.imcjms.com/registration/journal_full_text/193 |
| spellingShingle | Shaheda Anwar Md. Ruhul Amin Miah Ahmed Abu Saleh Humayun Sattar Sharmeen Ahmed Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city IMC Journal of Medical Science |
| title | Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city |
| title_full | Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city |
| title_fullStr | Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city |
| title_full_unstemmed | Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city |
| title_short | Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city |
| title_sort | phenotypic detection of metallo β lactamase among the clinical isolates of imipenem resistant pseudomonas and acinetobacter in tertiary care hospitals of dhaka city |
| url | http://www.imcjms.com/registration/journal_full_text/193 |
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