Gastric Diffuse Large B-Cell Lymphoma in an Adolescent: A Case Report
Non-Hodgkin lymphoma (NHL) is the 11th most common cancer worldwide and the 4th most common pediatric cancer. The GI tract is the most common extranodal site of NHL, making up about 30–40% of extranodal cases. The median age at diagnosis for gastrointestinal NHL (gNHL) is around 61. On the other han...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2023-02-01
|
| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/529181 |
| _version_ | 1811157617263771648 |
|---|---|
| author | Fouad Nahhat Kareem Zabad Hasan Najjar Modar Doyya Nisreen Khazeam |
| author_facet | Fouad Nahhat Kareem Zabad Hasan Najjar Modar Doyya Nisreen Khazeam |
| author_sort | Fouad Nahhat |
| collection | DOAJ |
| description | Non-Hodgkin lymphoma (NHL) is the 11th most common cancer worldwide and the 4th most common pediatric cancer. The GI tract is the most common extranodal site of NHL, making up about 30–40% of extranodal cases. The median age at diagnosis for gastrointestinal NHL (gNHL) is around 61. On the other hand, gNHL is very rare in the pediatric population. Herein, we report the case of a 15-year-old girl who complained of abdominal pain and vomiting after meals, with severe B symptoms (fever, night chills, and severe weight loss). Esophagogastroduodenoscopy showed a mass in the lesser curvature of the stomach. Subsequent biopsy and immunostaining of the sample confirmed the diagnosis of diffuse large B-cell lymphoma. CT and PET-CT scans indicated the involvement of mesenteric and lesser omental lymph nodes. Later on, the patient started an R-CHOP chemotherapy regimen. In this report, we aim to shine the light on such a rare disease in this age group. |
| first_indexed | 2024-04-10T05:10:15Z |
| format | Article |
| id | doaj.art-308e325076d64e4ab16ff7df60aa476a |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-04-10T05:10:15Z |
| publishDate | 2023-02-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-308e325076d64e4ab16ff7df60aa476a2023-03-09T08:59:35ZengKarger PublishersCase Reports in Oncology1662-65752023-02-01161636710.1159/000529181529181Gastric Diffuse Large B-Cell Lymphoma in an Adolescent: A Case ReportFouad Nahhat0https://orcid.org/0000-0002-8562-2954Kareem Zabad1Hasan Najjar2https://orcid.org/0000-0002-5128-9540Modar Doyya3Nisreen Khazeam4Faculty of Medicine, Damascus University, Damascus, Syrian Arab RepublicFaculty of Medicine, Damascus University, Damascus, Syrian Arab RepublicFaculty of Medicine, Damascus University, Damascus, Syrian Arab RepublicFaculty of Medicine, Damascus University, Damascus, Syrian Arab RepublicFaculty of Medicine, Damascus University, Damascus, Syrian Arab RepublicNon-Hodgkin lymphoma (NHL) is the 11th most common cancer worldwide and the 4th most common pediatric cancer. The GI tract is the most common extranodal site of NHL, making up about 30–40% of extranodal cases. The median age at diagnosis for gastrointestinal NHL (gNHL) is around 61. On the other hand, gNHL is very rare in the pediatric population. Herein, we report the case of a 15-year-old girl who complained of abdominal pain and vomiting after meals, with severe B symptoms (fever, night chills, and severe weight loss). Esophagogastroduodenoscopy showed a mass in the lesser curvature of the stomach. Subsequent biopsy and immunostaining of the sample confirmed the diagnosis of diffuse large B-cell lymphoma. CT and PET-CT scans indicated the involvement of mesenteric and lesser omental lymph nodes. Later on, the patient started an R-CHOP chemotherapy regimen. In this report, we aim to shine the light on such a rare disease in this age group.https://www.karger.com/Article/FullText/529181non-hodgkin lymphomadiffuse large b-cell lymphomagastric lymphomapediatric cancercase report |
| spellingShingle | Fouad Nahhat Kareem Zabad Hasan Najjar Modar Doyya Nisreen Khazeam Gastric Diffuse Large B-Cell Lymphoma in an Adolescent: A Case Report Case Reports in Oncology non-hodgkin lymphoma diffuse large b-cell lymphoma gastric lymphoma pediatric cancer case report |
| title | Gastric Diffuse Large B-Cell Lymphoma in an Adolescent: A Case Report |
| title_full | Gastric Diffuse Large B-Cell Lymphoma in an Adolescent: A Case Report |
| title_fullStr | Gastric Diffuse Large B-Cell Lymphoma in an Adolescent: A Case Report |
| title_full_unstemmed | Gastric Diffuse Large B-Cell Lymphoma in an Adolescent: A Case Report |
| title_short | Gastric Diffuse Large B-Cell Lymphoma in an Adolescent: A Case Report |
| title_sort | gastric diffuse large b cell lymphoma in an adolescent a case report |
| topic | non-hodgkin lymphoma diffuse large b-cell lymphoma gastric lymphoma pediatric cancer case report |
| url | https://www.karger.com/Article/FullText/529181 |
| work_keys_str_mv | AT fouadnahhat gastricdiffuselargebcelllymphomainanadolescentacasereport AT kareemzabad gastricdiffuselargebcelllymphomainanadolescentacasereport AT hasannajjar gastricdiffuselargebcelllymphomainanadolescentacasereport AT modardoyya gastricdiffuselargebcelllymphomainanadolescentacasereport AT nisreenkhazeam gastricdiffuselargebcelllymphomainanadolescentacasereport |