Exosomes in Liquid Biopsy: A Nanotool for Postradiotherapy Cancer Monitoring
Liquid biopsy has advantages over traditional biopsy, which cannot determine tumor dynamics. As a noninvasive and precise test, liquid biopsy detects biomarkers that carry information on tumor progression and has undergone tremendous development in recent years. Exosome detection is one of the metho...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2022-06-01
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| Series: | Frontiers in Bioscience-Landmark |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/FBL/27/7/10.31083/j.fbl2707205 |
| _version_ | 1818190874331316224 |
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| author | Yixin Shi Bingrun Qiu Linyang Huang Yiling Li Yiting Ze Yang Yao |
| author_facet | Yixin Shi Bingrun Qiu Linyang Huang Yiling Li Yiting Ze Yang Yao |
| author_sort | Yixin Shi |
| collection | DOAJ |
| description | Liquid biopsy has advantages over traditional biopsy, which cannot determine tumor dynamics. As a noninvasive and precise test, liquid biopsy detects biomarkers that carry information on tumor progression and has undergone tremendous development in recent years. Exosome detection is one of the methods of liquid biopsy. Radiotherapy affects the release of exosomes and intercellular communication. Based on the properties, extractability, and detectability of exosomes, key exosomal cargoes after tumor radiotherapy can be used as biomarkers for tumor prognosis. Exosomes after tumor radiotherapy can be used for liquid biopsy. The main applications include (1) predicting radiotherapy efficacy, (2) predicting tumor prognosis, and (3) optimizing the regimen of tumor treatment. This review provides further research directions for liquid biopsy after tumor radiotherapy. |
| first_indexed | 2024-12-12T00:05:39Z |
| format | Article |
| id | doaj.art-3090804927fc4233844fb6281f8d0980 |
| institution | Directory Open Access Journal |
| issn | 2768-6701 |
| language | English |
| last_indexed | 2024-12-12T00:05:39Z |
| publishDate | 2022-06-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Frontiers in Bioscience-Landmark |
| spelling | doaj.art-3090804927fc4233844fb6281f8d09802022-12-22T00:45:07ZengIMR PressFrontiers in Bioscience-Landmark2768-67012022-06-0127720510.31083/j.fbl2707205S2768-6701(22)00558-5Exosomes in Liquid Biopsy: A Nanotool for Postradiotherapy Cancer MonitoringYixin Shi0Bingrun Qiu1Linyang Huang2Yiling Li3Yiting Ze4Yang Yao5State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, 610041 Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, 610041 Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, 610041 Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, 610041 Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, 610041 Chengdu, Sichuan, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, 610041 Chengdu, Sichuan, ChinaLiquid biopsy has advantages over traditional biopsy, which cannot determine tumor dynamics. As a noninvasive and precise test, liquid biopsy detects biomarkers that carry information on tumor progression and has undergone tremendous development in recent years. Exosome detection is one of the methods of liquid biopsy. Radiotherapy affects the release of exosomes and intercellular communication. Based on the properties, extractability, and detectability of exosomes, key exosomal cargoes after tumor radiotherapy can be used as biomarkers for tumor prognosis. Exosomes after tumor radiotherapy can be used for liquid biopsy. The main applications include (1) predicting radiotherapy efficacy, (2) predicting tumor prognosis, and (3) optimizing the regimen of tumor treatment. This review provides further research directions for liquid biopsy after tumor radiotherapy.https://www.imrpress.com/journal/FBL/27/7/10.31083/j.fbl2707205exosomesliquid biopsycancerradiotherapy |
| spellingShingle | Yixin Shi Bingrun Qiu Linyang Huang Yiling Li Yiting Ze Yang Yao Exosomes in Liquid Biopsy: A Nanotool for Postradiotherapy Cancer Monitoring Frontiers in Bioscience-Landmark exosomes liquid biopsy cancer radiotherapy |
| title | Exosomes in Liquid Biopsy: A Nanotool for Postradiotherapy Cancer Monitoring |
| title_full | Exosomes in Liquid Biopsy: A Nanotool for Postradiotherapy Cancer Monitoring |
| title_fullStr | Exosomes in Liquid Biopsy: A Nanotool for Postradiotherapy Cancer Monitoring |
| title_full_unstemmed | Exosomes in Liquid Biopsy: A Nanotool for Postradiotherapy Cancer Monitoring |
| title_short | Exosomes in Liquid Biopsy: A Nanotool for Postradiotherapy Cancer Monitoring |
| title_sort | exosomes in liquid biopsy a nanotool for postradiotherapy cancer monitoring |
| topic | exosomes liquid biopsy cancer radiotherapy |
| url | https://www.imrpress.com/journal/FBL/27/7/10.31083/j.fbl2707205 |
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