Does Information from the Parkinson KinetiGraph™ (PKG) Influence the Neurologist’s Treatment Decisions?—An Observational Study in Routine Clinical Care of People with Parkinson’s Disease
Management of Parkinson’s disease traditionally relies solely on clinical assessment. The PKG objectively measures affected persons’ movements in daily life. The present study evaluated how often PKG data changed treatment decisions in routine clinical care and to what extent the clinical assessment...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-06-01
|
| Series: | Journal of Personalized Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4426/11/6/519 |
| _version_ | 1797531224657362944 |
|---|---|
| author | Mathias Sundgren Mattias Andréasson Per Svenningsson Rose-Marie Noori Anders Johansson |
| author_facet | Mathias Sundgren Mattias Andréasson Per Svenningsson Rose-Marie Noori Anders Johansson |
| author_sort | Mathias Sundgren |
| collection | DOAJ |
| description | Management of Parkinson’s disease traditionally relies solely on clinical assessment. The PKG objectively measures affected persons’ movements in daily life. The present study evaluated how often PKG data changed treatment decisions in routine clinical care and to what extent the clinical assessment and the PKG interpretation differed. PKG recordings were performed before routine visits. The neurologist first made a clinical assessment without reviewing the PKG. Signs and symptoms were recorded, and a treatment plan was documented. Afterward, the PKG was evaluated. Then, the neurologist decided whether to change the initial treatment plan or not. PKG review resulted in a change in the initial treatment plan in 21 of 66 participants (31.8%). The clinical assessment and the PKG review differed frequently, mainly regarding individual overall presence of motor problems (67%), profile of bradykinesia/wearing off (79%), dyskinesia (35%) and sleep (55%). PKG improved the dialogue with the participant in 88% of cases. PKG and clinical variables were stable when they were repeated after 3–6 months. In conclusion, PKG information changes treatment decisions in nearly a third of people with Parkinson’s disease in routine care. Standard clinical assessment and PKG evaluation are often non-identical. Objective measurements in people living with Parkinson’s disease can add therapeutically relevant information. |
| first_indexed | 2024-03-10T10:40:48Z |
| format | Article |
| id | doaj.art-30908929ad42405fbee195ce8ec49ed2 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-10T10:40:48Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-30908929ad42405fbee195ce8ec49ed22023-11-21T22:55:09ZengMDPI AGJournal of Personalized Medicine2075-44262021-06-0111651910.3390/jpm11060519Does Information from the Parkinson KinetiGraph™ (PKG) Influence the Neurologist’s Treatment Decisions?—An Observational Study in Routine Clinical Care of People with Parkinson’s DiseaseMathias Sundgren0Mattias Andréasson1Per Svenningsson2Rose-Marie Noori3Anders Johansson4Department of Neurology, Karolinska University Hospital, 171 64 Stockholm, SwedenDepartment of Neurology, Karolinska University Hospital, 171 64 Stockholm, SwedenDepartment of Neurology, Karolinska University Hospital, 171 64 Stockholm, SwedenDepartment of Neurology, Karolinska University Hospital, 171 64 Stockholm, SwedenDepartment of Neurology, Karolinska University Hospital, 171 64 Stockholm, SwedenManagement of Parkinson’s disease traditionally relies solely on clinical assessment. The PKG objectively measures affected persons’ movements in daily life. The present study evaluated how often PKG data changed treatment decisions in routine clinical care and to what extent the clinical assessment and the PKG interpretation differed. PKG recordings were performed before routine visits. The neurologist first made a clinical assessment without reviewing the PKG. Signs and symptoms were recorded, and a treatment plan was documented. Afterward, the PKG was evaluated. Then, the neurologist decided whether to change the initial treatment plan or not. PKG review resulted in a change in the initial treatment plan in 21 of 66 participants (31.8%). The clinical assessment and the PKG review differed frequently, mainly regarding individual overall presence of motor problems (67%), profile of bradykinesia/wearing off (79%), dyskinesia (35%) and sleep (55%). PKG improved the dialogue with the participant in 88% of cases. PKG and clinical variables were stable when they were repeated after 3–6 months. In conclusion, PKG information changes treatment decisions in nearly a third of people with Parkinson’s disease in routine care. Standard clinical assessment and PKG evaluation are often non-identical. Objective measurements in people living with Parkinson’s disease can add therapeutically relevant information.https://www.mdpi.com/2075-4426/11/6/519Parkinson’s diseaseobjective measurementPKGdevicetreatment |
| spellingShingle | Mathias Sundgren Mattias Andréasson Per Svenningsson Rose-Marie Noori Anders Johansson Does Information from the Parkinson KinetiGraph™ (PKG) Influence the Neurologist’s Treatment Decisions?—An Observational Study in Routine Clinical Care of People with Parkinson’s Disease Journal of Personalized Medicine Parkinson’s disease objective measurement PKG device treatment |
| title | Does Information from the Parkinson KinetiGraph™ (PKG) Influence the Neurologist’s Treatment Decisions?—An Observational Study in Routine Clinical Care of People with Parkinson’s Disease |
| title_full | Does Information from the Parkinson KinetiGraph™ (PKG) Influence the Neurologist’s Treatment Decisions?—An Observational Study in Routine Clinical Care of People with Parkinson’s Disease |
| title_fullStr | Does Information from the Parkinson KinetiGraph™ (PKG) Influence the Neurologist’s Treatment Decisions?—An Observational Study in Routine Clinical Care of People with Parkinson’s Disease |
| title_full_unstemmed | Does Information from the Parkinson KinetiGraph™ (PKG) Influence the Neurologist’s Treatment Decisions?—An Observational Study in Routine Clinical Care of People with Parkinson’s Disease |
| title_short | Does Information from the Parkinson KinetiGraph™ (PKG) Influence the Neurologist’s Treatment Decisions?—An Observational Study in Routine Clinical Care of People with Parkinson’s Disease |
| title_sort | does information from the parkinson kinetigraph™ pkg influence the neurologist s treatment decisions an observational study in routine clinical care of people with parkinson s disease |
| topic | Parkinson’s disease objective measurement PKG device treatment |
| url | https://www.mdpi.com/2075-4426/11/6/519 |
| work_keys_str_mv | AT mathiassundgren doesinformationfromtheparkinsonkinetigraphpkginfluencetheneurologiststreatmentdecisionsanobservationalstudyinroutineclinicalcareofpeoplewithparkinsonsdisease AT mattiasandreasson doesinformationfromtheparkinsonkinetigraphpkginfluencetheneurologiststreatmentdecisionsanobservationalstudyinroutineclinicalcareofpeoplewithparkinsonsdisease AT persvenningsson doesinformationfromtheparkinsonkinetigraphpkginfluencetheneurologiststreatmentdecisionsanobservationalstudyinroutineclinicalcareofpeoplewithparkinsonsdisease AT rosemarienoori doesinformationfromtheparkinsonkinetigraphpkginfluencetheneurologiststreatmentdecisionsanobservationalstudyinroutineclinicalcareofpeoplewithparkinsonsdisease AT andersjohansson doesinformationfromtheparkinsonkinetigraphpkginfluencetheneurologiststreatmentdecisionsanobservationalstudyinroutineclinicalcareofpeoplewithparkinsonsdisease |