Synthetic Pinnatoxins A and G Reversibly Block Mouse Skeletal Neuromuscular Transmission In Vivo and In Vitro

Pinnatoxins (PnTXs) A-H constitute an emerging family belonging to the cyclic imine group of phycotoxins. Interest has been focused on these fast-acting and highly-potent toxins because they are widely found in contaminated shellfish. Despite their highly complex molecular structure, PnTXs have been...

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Bibliographic Details
Main Authors: Evelyne Benoit, Aurélie Couesnon, Jiri Lindovsky, Bogdan I. Iorga, Rómulo Aráoz, Denis Servent, Armen Zakarian, Jordi Molgó
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/17/5/306

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