Protective Effect of Shikimic Acid against Cisplatin-Induced Renal Injury: In Vitro and In Vivo Studies

Protective Effect of Shikimic Acid against Cisplatin-Induced Renal Injury: In Vitro and In Vivo Studies

Nephrotoxicity is a serious side effect of cisplatin, which is one of the most frequently used drugs for cancer treatment. This study aimed to assess the renoprotective effect of <i>Artemisia absinthium</i> extract and its bioactive compound (shikimic acid) against cisplatin-induced rena...

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Bibliographic Details
Main Authors: Jinkyung Lee, Quynh Nhu Nguyen, Jun Yeon Park, Sullim Lee, Gwi Seo Hwang, Noriko Yamabe, Sungyoul Choi, Ki Sung Kang
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Plants
Subjects:
<i>Artemisia absinthium</i>
shikimic acid
cisplatin
nephrotoxicity
apoptosis
Online Access:https://www.mdpi.com/2223-7747/9/12/1681

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