The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma

The pursuit of matrix metalloproteinase (MMP) inhibitors began in earnest over three decades ago. Initial clinical trials were disappointing, resulting in a negative view of MMPs as therapeutic targets. As a better understanding of MMP biology and inhibitor pharmacokinetic properties emerged, it bec...

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Hlavní autor: Gregg B. Fields
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2019-08-01
Edice:Cells
Témata:
On-line přístup:https://www.mdpi.com/2073-4409/8/9/984