Disability of Dialysis Patients and the Condition of Blood Vessels
The number of elderly hemodialysis patients is constantly increasing worldwide. This population has a high burden of comorbid conditions, which impair daily activities. The aim of the study was to analyze problems of disability in hemodialysis patients in the context of cardiovascular (CV) complicat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/6/1806 |
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| author | Tomasz Gołębiowski Mariusz Kusztal Andrzej Konieczny Krzysztof Letachowicz Ada Gawryś Beata Skolimowska Bożena Ostrowska Sławomir Zmonarski Dariusz Janczak Magdalena Krajewska |
| author_facet | Tomasz Gołębiowski Mariusz Kusztal Andrzej Konieczny Krzysztof Letachowicz Ada Gawryś Beata Skolimowska Bożena Ostrowska Sławomir Zmonarski Dariusz Janczak Magdalena Krajewska |
| author_sort | Tomasz Gołębiowski |
| collection | DOAJ |
| description | The number of elderly hemodialysis patients is constantly increasing worldwide. This population has a high burden of comorbid conditions, which impair daily activities. The aim of the study was to analyze problems of disability in hemodialysis patients in the context of cardiovascular (CV) complications and vascular condition. In this cross-sectional study, 129 patients (mean age 64.5) were enrolled. The degree of disability in Barthel index (Bi) and 10-year cardiovascular risk (QRISK<sup>®</sup>3) were assessed. A Mobil-O-Graph monitor was used for measuring hemodynamic parameters. Only 6.2% of patients were professionally active, 19% used a wheelchair for transport, and 16% used crutches. More than half (51%) were independent in everyday activities reaching 80–100 points on Bi. The rest, with Bi < 80, were considered as dependent. The most common causes of disability were CV complications. The independent group (80–100 points) was characterized by significantly lower pulse wave velocity (PWV) and lower QRISK<sup>®</sup>3 compared to dependent patients. The degree of disability negatively correlated with age, PWV, and QRISK<sup>®</sup>3. Multivariate logistic regression revealed that disability (Bi < 80) was independently associated with CV events in the past adjusted odds ratio (adj.OR) 4.83 (95% confidence interval (95% CI): 1.74–13.41) and higher PWV adj.OR 1.45 (95% CI: 1.15–1.82). Our results indicate that CV diseases are the most important cause of functional impairment. |
| first_indexed | 2024-03-10T19:15:47Z |
| format | Article |
| id | doaj.art-30a665152726430fb5e3a759143ea7e7 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T19:15:47Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-30a665152726430fb5e3a759143ea7e72023-11-20T03:24:30ZengMDPI AGJournal of Clinical Medicine2077-03832020-06-0196180610.3390/jcm9061806Disability of Dialysis Patients and the Condition of Blood VesselsTomasz Gołębiowski0Mariusz Kusztal1Andrzej Konieczny2Krzysztof Letachowicz3Ada Gawryś4Beata Skolimowska5Bożena Ostrowska6Sławomir Zmonarski7Dariusz Janczak8Magdalena Krajewska9Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Occupational Therapy, University School of Physical Education in Wroclaw, 51-612 Wroclaw, PolandDepartment of Occupational Therapy, University School of Physical Education in Wroclaw, 51-612 Wroclaw, PolandDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Vascular, General and Transplantation Surgery, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, PolandThe number of elderly hemodialysis patients is constantly increasing worldwide. This population has a high burden of comorbid conditions, which impair daily activities. The aim of the study was to analyze problems of disability in hemodialysis patients in the context of cardiovascular (CV) complications and vascular condition. In this cross-sectional study, 129 patients (mean age 64.5) were enrolled. The degree of disability in Barthel index (Bi) and 10-year cardiovascular risk (QRISK<sup>®</sup>3) were assessed. A Mobil-O-Graph monitor was used for measuring hemodynamic parameters. Only 6.2% of patients were professionally active, 19% used a wheelchair for transport, and 16% used crutches. More than half (51%) were independent in everyday activities reaching 80–100 points on Bi. The rest, with Bi < 80, were considered as dependent. The most common causes of disability were CV complications. The independent group (80–100 points) was characterized by significantly lower pulse wave velocity (PWV) and lower QRISK<sup>®</sup>3 compared to dependent patients. The degree of disability negatively correlated with age, PWV, and QRISK<sup>®</sup>3. Multivariate logistic regression revealed that disability (Bi < 80) was independently associated with CV events in the past adjusted odds ratio (adj.OR) 4.83 (95% confidence interval (95% CI): 1.74–13.41) and higher PWV adj.OR 1.45 (95% CI: 1.15–1.82). Our results indicate that CV diseases are the most important cause of functional impairment.https://www.mdpi.com/2077-0383/9/6/1806hemodialysisdisabilityend-stage renal diseasearterial stiffnesspulse wave velocity |
| spellingShingle | Tomasz Gołębiowski Mariusz Kusztal Andrzej Konieczny Krzysztof Letachowicz Ada Gawryś Beata Skolimowska Bożena Ostrowska Sławomir Zmonarski Dariusz Janczak Magdalena Krajewska Disability of Dialysis Patients and the Condition of Blood Vessels Journal of Clinical Medicine hemodialysis disability end-stage renal disease arterial stiffness pulse wave velocity |
| title | Disability of Dialysis Patients and the Condition of Blood Vessels |
| title_full | Disability of Dialysis Patients and the Condition of Blood Vessels |
| title_fullStr | Disability of Dialysis Patients and the Condition of Blood Vessels |
| title_full_unstemmed | Disability of Dialysis Patients and the Condition of Blood Vessels |
| title_short | Disability of Dialysis Patients and the Condition of Blood Vessels |
| title_sort | disability of dialysis patients and the condition of blood vessels |
| topic | hemodialysis disability end-stage renal disease arterial stiffness pulse wave velocity |
| url | https://www.mdpi.com/2077-0383/9/6/1806 |
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