Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinoma

Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinoma

Abstract Background Cystatins are a class of proteins that can inhibit cysteine protease and are widely distributed in human bodily fluids and secretions. Cystatin SN (CST1), a member of the CST superfamily, is abnormally expressed in a variety of tumors. However, its effect on the occurrence and de...

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Bibliographic Details
Main Authors: Jian Yang, Gaomeng Luo, Chang Li, Zhunlin Zhao, Sheng Ju, Qifan Li, Zhike Chen, Cheng Ding, Xin Tong, Jun Zhao
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Cancer
Subjects:
Lung adenocarcinoma
Epithelial-mesenchymal transition (EMT)
Tumor immune microenvironment (TIME)
Cystatin SN (CST1)
Biomarker
Online Access:https://doi.org/10.1186/s12885-022-09685-z

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