Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei)
An organic extract from fresh shrimp (Litopenaeus vannamei) was studied for antimutagenic and antiproliferative properties using Salmonella typhimurium tester strains TA98 and TA100 with metabolic activation (S9) and a cancer cell line (B-cell lymphoma), respectively. Shrimp extract was sequentially...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-11-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/8/11/2795/ |
| _version_ | 1811184757933867008 |
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| author | Carolina Moreno-Félix Carlos Velazquez Maribel Plascencia-Jatomea Anita Acosta Lorena Machi-Lara María-Lourdes Aldana-Madrid Josafat-Marina Ezquerra-Brauer Ramón Robles-Zepeda Armando Burgos-Hernandez Griselda Wilson-Sanchez |
| author_facet | Carolina Moreno-Félix Carlos Velazquez Maribel Plascencia-Jatomea Anita Acosta Lorena Machi-Lara María-Lourdes Aldana-Madrid Josafat-Marina Ezquerra-Brauer Ramón Robles-Zepeda Armando Burgos-Hernandez Griselda Wilson-Sanchez |
| author_sort | Carolina Moreno-Félix |
| collection | DOAJ |
| description | An organic extract from fresh shrimp (Litopenaeus vannamei) was studied for antimutagenic and antiproliferative properties using Salmonella typhimurium tester strains TA98 and TA100 with metabolic activation (S9) and a cancer cell line (B-cell lymphoma), respectively. Shrimp extract was sequentially fractionated by thin layer chromatography (TLC) and each fraction was tested for antimutagenic and antiproliferative activities. Crude organic extracts obtained from shrimp reduced the number of revertants caused by aflatoxina B1, showing a dose-response type of relationship. Sequential TLC fractionation of the active extracts produced several antimutagenic and/or antiproliferative fractions. These results suggested that the lipid fraction of the tested species contained compounds with chemoprotective properties that reduce the mutagenicity of AFB1 and proliferation of a cancer cell line. |
| first_indexed | 2024-04-11T13:17:51Z |
| format | Article |
| id | doaj.art-30ab56d8867d4563b9397a9ba7a78957 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T13:17:51Z |
| publishDate | 2010-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-30ab56d8867d4563b9397a9ba7a789572022-12-22T04:22:19ZengMDPI AGMarine Drugs1660-33972010-11-018112795280910.3390/md8112795Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei)Carolina Moreno-FélixCarlos VelazquezMaribel Plascencia-JatomeaAnita AcostaLorena Machi-LaraMaría-Lourdes Aldana-MadridJosafat-Marina Ezquerra-BrauerRamón Robles-ZepedaArmando Burgos-HernandezGriselda Wilson-SanchezAn organic extract from fresh shrimp (Litopenaeus vannamei) was studied for antimutagenic and antiproliferative properties using Salmonella typhimurium tester strains TA98 and TA100 with metabolic activation (S9) and a cancer cell line (B-cell lymphoma), respectively. Shrimp extract was sequentially fractionated by thin layer chromatography (TLC) and each fraction was tested for antimutagenic and antiproliferative activities. Crude organic extracts obtained from shrimp reduced the number of revertants caused by aflatoxina B1, showing a dose-response type of relationship. Sequential TLC fractionation of the active extracts produced several antimutagenic and/or antiproliferative fractions. These results suggested that the lipid fraction of the tested species contained compounds with chemoprotective properties that reduce the mutagenicity of AFB1 and proliferation of a cancer cell line.http://www.mdpi.com/1660-3397/8/11/2795/antimutagenicityantiproliferationcultured shrimp |
| spellingShingle | Carolina Moreno-Félix Carlos Velazquez Maribel Plascencia-Jatomea Anita Acosta Lorena Machi-Lara María-Lourdes Aldana-Madrid Josafat-Marina Ezquerra-Brauer Ramón Robles-Zepeda Armando Burgos-Hernandez Griselda Wilson-Sanchez Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei) Marine Drugs antimutagenicity antiproliferation cultured shrimp |
| title | Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei) |
| title_full | Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei) |
| title_fullStr | Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei) |
| title_full_unstemmed | Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei) |
| title_short | Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei) |
| title_sort | antimutagenicity and antiproliferative studies of lipidic extracts from white shrimp litopenaeus vannamei |
| topic | antimutagenicity antiproliferation cultured shrimp |
| url | http://www.mdpi.com/1660-3397/8/11/2795/ |
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