Spatiotemporal Expression of SphK1 and S1PR2 in the Hippocampus of Pilocarpine Rat Model and the Epileptic Foci of Temporal Lobe Epilepsy

Spatiotemporal Expression of SphK1 and S1PR2 in the Hippocampus of Pilocarpine Rat Model and the Epileptic Foci of Temporal Lobe Epilepsy

Temporal lobe epilepsy (TLE) is a severe chronic neurological disease caused by abnormal discharge of neurons in the brain and seriously affect the long-term life quality of patients. Currently, new insights into the pathogenesis of TLE are urgently needed to provide more personalized and effective...

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Bibliographic Details
Main Authors: Yuan-Yuan Dong, Min Xia, Lin Wang, Shuai Cui, Qiu-Bo Li, Jun-Chen Zhang, Shu-Shu Meng, Yan-Ke Zhang, Qing-Xia Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
temporal lobe epilepsy
SphK1
S1PR2
astrocyte
neuron
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00800/full

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