A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children

Abstract Background Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-effectiveness of home safety interventions...

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Main Authors: Felix Achana, Alex J. Sutton, Denise Kendrick, Mike Hayes, David R. Jones, Stephanie J. Hubbard, Nicola J. Cooper
Format: Article
Language:English
Published: BMC 2016-08-01
Series:BMC Public Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12889-016-3334-0
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author Felix Achana
Alex J. Sutton
Denise Kendrick
Mike Hayes
David R. Jones
Stephanie J. Hubbard
Nicola J. Cooper
author_facet Felix Achana
Alex J. Sutton
Denise Kendrick
Mike Hayes
David R. Jones
Stephanie J. Hubbard
Nicola J. Cooper
author_sort Felix Achana
collection DOAJ
description Abstract Background Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-effectiveness of home safety interventions to promote poison prevention practices. Methods A probabilistic decision-analytic model simulates healthcare costs and benefits for a hypothetical cohort of under 5 year olds. The model compares the cost-effectiveness of home safety education, home safety inspections, provision of free or low cost safety equipment and fitting of equipment. Analyses are conducted from a UK National Health Service and Personal Social Services perspective and expressed in 2012 prices. Results Education without safety inspection, provision or fitting of equipment was the most cost-effective strategy for promoting safe storage of medicines with an incremental cost-effectiveness ratio of £2888 (95 % credible interval (CrI) £1990–£5774) per poison case avoided or £41,330 (95%CrI £20,007–£91,534) per QALY gained compared with usual care. Compared to usual care, home safety interventions were not cost-effective in promoting safe storage of other household products. Conclusion Education offers better value for money than more intensive but expensive strategies for preventing medicinal poisonings, but is only likely to be cost-effective at £30,000 per QALY gained for families in disadvantaged areas and for those with more than one child. There was considerable uncertainty in cost-effectiveness estimates due to paucity of evidence on model parameters. Policy makers should consider both costs and effectiveness of competing interventions to ensure efficient use of resources.
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spelling doaj.art-30b2d16973544643b3787493ef1447832022-12-21T22:37:21ZengBMCBMC Public Health1471-24582016-08-0116111710.1186/s12889-016-3334-0A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young childrenFelix Achana0Alex J. Sutton1Denise Kendrick2Mike Hayes3David R. Jones4Stephanie J. Hubbard5Nicola J. Cooper6Clinical Trials Unit, Warwick Medical School, University of WarwickDepartment of Health Sciences, University of LeicesterDivision of Primary Care, University of NottinghamChild Accident Prevention TrustDepartment of Health Sciences, University of LeicesterDepartment of Health Sciences, University of LeicesterDepartment of Health Sciences, University of LeicesterAbstract Background Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-effectiveness of home safety interventions to promote poison prevention practices. Methods A probabilistic decision-analytic model simulates healthcare costs and benefits for a hypothetical cohort of under 5 year olds. The model compares the cost-effectiveness of home safety education, home safety inspections, provision of free or low cost safety equipment and fitting of equipment. Analyses are conducted from a UK National Health Service and Personal Social Services perspective and expressed in 2012 prices. Results Education without safety inspection, provision or fitting of equipment was the most cost-effective strategy for promoting safe storage of medicines with an incremental cost-effectiveness ratio of £2888 (95 % credible interval (CrI) £1990–£5774) per poison case avoided or £41,330 (95%CrI £20,007–£91,534) per QALY gained compared with usual care. Compared to usual care, home safety interventions were not cost-effective in promoting safe storage of other household products. Conclusion Education offers better value for money than more intensive but expensive strategies for preventing medicinal poisonings, but is only likely to be cost-effective at £30,000 per QALY gained for families in disadvantaged areas and for those with more than one child. There was considerable uncertainty in cost-effectiveness estimates due to paucity of evidence on model parameters. Policy makers should consider both costs and effectiveness of competing interventions to ensure efficient use of resources.http://link.springer.com/article/10.1186/s12889-016-3334-0Economic evaluationPublic healthInjury preventionPoisoningsChildrenDecision models
spellingShingle Felix Achana
Alex J. Sutton
Denise Kendrick
Mike Hayes
David R. Jones
Stephanie J. Hubbard
Nicola J. Cooper
A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children
BMC Public Health
Economic evaluation
Public health
Injury prevention
Poisonings
Children
Decision models
title A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children
title_full A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children
title_fullStr A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children
title_full_unstemmed A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children
title_short A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children
title_sort decision analytic model to investigate the cost effectiveness of poisoning prevention practices in households with young children
topic Economic evaluation
Public health
Injury prevention
Poisonings
Children
Decision models
url http://link.springer.com/article/10.1186/s12889-016-3334-0
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