Evaluation of the effect of liposomal miR-143 on cell viability and anti-apoptotic gene expression of Bcl-2 in human osteosarcoma cells for the treatment of metastatic cancers

Evaluation of the effect of liposomal miR-143 on cell viability and anti-apoptotic gene expression of Bcl-2 in human osteosarcoma cells for the treatment of metastatic cancers

Introdution: The present study was conducted to evaluate the effect of miR-143 on the expression of Bcl2 gene at the level of mRNA, cell cytotoxicity in the SaOs-2 cell line (Osteosarcoma) and Hum 63 (Human primary bone cells). Methods: In this experimental study, miR-143 was introduced into the SaO...

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Bibliographic Details
Main Authors: fatemeh Barzegari firouzabadi, Shahrbanoo oryan, Mohammad Hasan Sheikhha, Seyed Mehdi Kalantar, Ameneh Javed
Format: Article
Language:fas
Published: Shahid Sadoughi University of Medical Sciences 2018-10-01
Series:Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Subjects:
miR-143
Lipofectamin
Bcl-2
Osteosarcoma.
Online Access:http://jssu.ssu.ac.ir/browse.php?a_code=A-10-303-5&slc_lang=en&sid=1

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