Epigenetic-Transcriptional Regulation of Fatty Acid Metabolism and Its Alterations in Leukaemia

Epigenetic-Transcriptional Regulation of Fatty Acid Metabolism and Its Alterations in Leukaemia

In recent years fatty acid metabolism has gained greater attention in haematologic cancers such as acute myeloid leukaemia. The oxidation of fatty acids provides fuel in the form of ATP and NADH, while fatty acid synthesis provides building blocks for cellular structures. Here, we will discuss how l...

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Bibliographic Details
Main Authors: Michael Maher, Jeannine Diesch, Raquel Casquero, Marcus Buschbeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Genetics
Subjects:
cancer
AML
fatty acid metabolism
fatty acid oxidation
epigenetics
CPT1
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00405/full

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