Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis

The article describes a clinical observation of the effective treatment of a multimorbid HIV positive patient with multiple drug resistant tuberculosis. It demonstrates modern approaches to treatment and optimal chemotherapy regimens containing bedaquiline. In the treatment of patients with a combina...

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Main Authors: E. M. Zhukova, E. V. Kulchavenya
Format: Article
Language:Russian
Published: New Terra Publishing House 2022-07-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/1651
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author E. M. Zhukova
E. V. Kulchavenya
author_facet E. M. Zhukova
E. V. Kulchavenya
author_sort E. M. Zhukova
collection DOAJ
description The article describes a clinical observation of the effective treatment of a multimorbid HIV positive patient with multiple drug resistant tuberculosis. It demonstrates modern approaches to treatment and optimal chemotherapy regimens containing bedaquiline. In the treatment of patients with a combination of chronic infectious diseases (tuberculosis, HIV infection, parenteral hepatitis) and oncological pathology (kidney cancer), interdepartmental interaction of specialists (phthisiologists, infectious disease specialists, and oncologists) is needed in order to compile successful treatment regimens taking into account multiple comorbidities and the risk of adverse reactions to drug combinations and choose the right time to perform a successful surgery.
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spelling doaj.art-30b87ed59143473e84467c74ebdfcc842023-09-03T13:29:08ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062022-07-011006535810.21292/2075-1230-2022-100-6-53-581646Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosisE. M. Zhukova0E. V. Kulchavenya11ФГБУ «Новосибирский НИИ туберкулеза» МЗ РФ1ФГБУ «Новосибирский НИИ туберкулеза» МЗ РФ; ФГБОУВО «Новосибирский государственный медицинский университете» МЗ РФThe article describes a clinical observation of the effective treatment of a multimorbid HIV positive patient with multiple drug resistant tuberculosis. It demonstrates modern approaches to treatment and optimal chemotherapy regimens containing bedaquiline. In the treatment of patients with a combination of chronic infectious diseases (tuberculosis, HIV infection, parenteral hepatitis) and oncological pathology (kidney cancer), interdepartmental interaction of specialists (phthisiologists, infectious disease specialists, and oncologists) is needed in order to compile successful treatment regimens taking into account multiple comorbidities and the risk of adverse reactions to drug combinations and choose the right time to perform a successful surgery.https://www.tibl-journal.com/jour/article/view/1651туберкулезвич-инфекциямножественная лекарственная устойчивостьхимиотерапиярак почки
spellingShingle E. M. Zhukova
E. V. Kulchavenya
Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis
Туберкулез и болезни лёгких
туберкулез
вич-инфекция
множественная лекарственная устойчивость
химиотерапия
рак почки
title Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis
title_full Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis
title_fullStr Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis
title_full_unstemmed Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis
title_short Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis
title_sort efcacy and safety of combination therapy with bedaquiline in a multimorbid hiv positive patient with multiple drug resistant tuberculosis
topic туберкулез
вич-инфекция
множественная лекарственная устойчивость
химиотерапия
рак почки
url https://www.tibl-journal.com/jour/article/view/1651
work_keys_str_mv AT emzhukova efcacyandsafetyofcombinationtherapywithbedaquilineinamultimorbidhivpositivepatientwithmultipledrugresistanttuberculosis
AT evkulchavenya efcacyandsafetyofcombinationtherapywithbedaquilineinamultimorbidhivpositivepatientwithmultipledrugresistanttuberculosis