Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis
The article describes a clinical observation of the effective treatment of a multimorbid HIV positive patient with multiple drug resistant tuberculosis. It demonstrates modern approaches to treatment and optimal chemotherapy regimens containing bedaquiline. In the treatment of patients with a combina...
Main Authors: | , |
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Format: | Article |
Language: | Russian |
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New Terra Publishing House
2022-07-01
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Series: | Туберкулез и болезни лёгких |
Subjects: | |
Online Access: | https://www.tibl-journal.com/jour/article/view/1651 |
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author | E. M. Zhukova E. V. Kulchavenya |
author_facet | E. M. Zhukova E. V. Kulchavenya |
author_sort | E. M. Zhukova |
collection | DOAJ |
description | The article describes a clinical observation of the effective treatment of a multimorbid HIV positive patient with multiple drug resistant tuberculosis. It demonstrates modern approaches to treatment and optimal chemotherapy regimens containing bedaquiline. In the treatment of patients with a combination of chronic infectious diseases (tuberculosis, HIV infection, parenteral hepatitis) and oncological pathology (kidney cancer), interdepartmental interaction of specialists (phthisiologists, infectious disease specialists, and oncologists) is needed in order to compile successful treatment regimens taking into account multiple comorbidities and the risk of adverse reactions to drug combinations and choose the right time to perform a successful surgery. |
first_indexed | 2024-03-12T03:29:39Z |
format | Article |
id | doaj.art-30b87ed59143473e84467c74ebdfcc84 |
institution | Directory Open Access Journal |
issn | 2075-1230 2542-1506 |
language | Russian |
last_indexed | 2025-03-14T09:56:36Z |
publishDate | 2022-07-01 |
publisher | New Terra Publishing House |
record_format | Article |
series | Туберкулез и болезни лёгких |
spelling | doaj.art-30b87ed59143473e84467c74ebdfcc842025-03-02T11:22:35ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062022-07-011006535810.21292/2075-1230-2022-100-6-53-581646Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosisE. M. Zhukova0E. V. Kulchavenya1Novosibirsk Tuberculosis Research InstituteNovosibirsk Tuberculosis Research Institute; Novosibirsk State Medical UniversityThe article describes a clinical observation of the effective treatment of a multimorbid HIV positive patient with multiple drug resistant tuberculosis. It demonstrates modern approaches to treatment and optimal chemotherapy regimens containing bedaquiline. In the treatment of patients with a combination of chronic infectious diseases (tuberculosis, HIV infection, parenteral hepatitis) and oncological pathology (kidney cancer), interdepartmental interaction of specialists (phthisiologists, infectious disease specialists, and oncologists) is needed in order to compile successful treatment regimens taking into account multiple comorbidities and the risk of adverse reactions to drug combinations and choose the right time to perform a successful surgery.https://www.tibl-journal.com/jour/article/view/1651tuberculosishiv infectionmultiple drug resistancechemotherapykidney cancer |
spellingShingle | E. M. Zhukova E. V. Kulchavenya Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis Туберкулез и болезни лёгких tuberculosis hiv infection multiple drug resistance chemotherapy kidney cancer |
title | Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis |
title_full | Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis |
title_fullStr | Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis |
title_full_unstemmed | Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis |
title_short | Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis |
title_sort | efcacy and safety of combination therapy with bedaquiline in a multimorbid hiv positive patient with multiple drug resistant tuberculosis |
topic | tuberculosis hiv infection multiple drug resistance chemotherapy kidney cancer |
url | https://www.tibl-journal.com/jour/article/view/1651 |
work_keys_str_mv | AT emzhukova efcacyandsafetyofcombinationtherapywithbedaquilineinamultimorbidhivpositivepatientwithmultipledrugresistanttuberculosis AT evkulchavenya efcacyandsafetyofcombinationtherapywithbedaquilineinamultimorbidhivpositivepatientwithmultipledrugresistanttuberculosis |