Synergistic effects of low-dose arsenic and N-methyl-N′-nitro-N-nitrosoguanidine co-exposure by altering gut microbiota and intestinal metabolic profile in rats

Synergistic effects of low-dose arsenic and N-methyl-N′-nitro-N-nitrosoguanidine co-exposure by altering gut microbiota and intestinal metabolic profile in rats

Biological organisms are exposed to low-dose arsenic or N-nitro compounds (NOCs) alone or in combination worldwide, especially in areas with high cancer prevalence through drinking water or food exposure; however, information on their combined exposure effects is limited. Here, we conducted an in-de...

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Bibliographic Details
Main Authors: Kexin Wang, Xiao Lin, Tingting Wang, Xiaohui Zhang, Wenli Cheng, Fang Xu, Li Wang, Bin Li, Min Wang, Wuqi Wang, Meng Zhang, Shaopeng Ding, Guoqing Jin, Yuting Zhu, Wanshui Yang, Anla Hu, Qihong Zhao
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Arsenic
MNNG
Co-exposure
Gut microbiota
Intestinal metabolic
Carcinogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323006991

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