Impact of omega-3 fatty acids supplementation on the gene expression of peroxisome proliferator activated receptors-γ, α and fibroblast growth factor-21 serum levels in patients with various presentation of metabolic conditions: a GRADE assessed systematic review and dose–response meta-analysis of clinical trials

Impact of omega-3 fatty acids supplementation on the gene expression of peroxisome proliferator activated receptors-γ, α and fibroblast growth factor-21 serum levels in patients with various presentation of metabolic conditions: a GRADE assessed systematic review and dose–response meta-analysis of clinical trials

There is some debate about the effects of omega-3 fatty acids on the regulation of adipose tissue related genes. This systematic review and meta-analysis aimed to evaluate the effects of omega-3 fatty acids supplementation on the gene expression of peroxisome proliferator activated receptors (PPAR-α...

Full description

Bibliographic Details
Main Authors:	Amirhossein Ramezani Ahmadi, Fatemeh Shirani, Behnazi Abiri, Mansoor Siavash, Sasan Haghighi, Mojtaba Akbari
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Nutrition
Subjects:	n-3 fatty acids polyunsaturated fatty acids PUFA PPAR fibroblast growth regulatory factor
Online Access:	https://www.frontiersin.org/articles/10.3389/fnut.2023.1202688/full

Similar Items

Causal effects of fatty acids on depression: Mendelian randomization study
by: Lingsi Zeng, et al.
Published: (2022-12-01)

A Critical Look at Omega-3 Supplementation: A Thematic Review
by: Yamil Liscano, et al.
Published: (2023-11-01)

The Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer
by: Mayra Montecillo-Aguado, et al.
Published: (2023-07-01)

Role of diets rich in omega-3 and omega-6 in the development of cancer
by: Sara Huerta-Yépez, et al.
Published: (2016-11-01)

Correlations between omega-3 fatty acids and inflammatory/glial abnormalities: the involvement of the membrane and neurotransmitter dysfunction in schizophrenia
by: Yongping Zhang, et al.
Published: (2023-10-01)

Whole blood fatty acid profile of young subjects and adherence to the Mediterranean diet: an observational cohort study
by: Marie-Louise Syrén, et al.
Published: (2022-02-01)

Deuterated polyunsaturated fatty acids reduce oxidative stress and extend the lifespan of C. elegans
by: Beaudoin-Chabot, Caroline, et al.
Published: (2020)

The association between polyunsaturated fatty acids and depression among Iranian postgraduate students in Malaysia
by: Aazami Sanaz, et al.
Published: (2011-08-01)

The influence of dietary and supplemental omega-3 fatty acids on the omega-3 index: A scoping review
by: Meghan Dempsey, et al.
Published: (2023-01-01)

Biophysical modeling indicates a high affinity of ethyl esters of omega-3 polyunsaturated fatty acids to the enzymes of the pro-inflammatory arachidonic acid cascade
by: I. Yu. Torshin, et al.
Published: (2022-07-01)

The amount of monounsaturated, polyunsaturated, and saturated fatty acids in the diet of fifteen-year-olds boys and girls in correlation with body mass index values
by: Wioletta Waksmańska, et al.
Published: (2021-03-01)

Commentary: Fish and the thyroid: A Janus Bifrons relationship caused by pollutants and the omega-3 polyunsaturated fatty acids
by: Silvana Hrelia, et al.
Published: (2023-04-01)

Characterization of lipid productivity and fatty acid profile of three fast-growing microalgae isolated from Bengkulu for possible use in health application
by: Swastika Praharyawan, et al.
Published: (2016-05-01)

Fatty Acid Synthesis by Indonesian Marine Diatom, Chaetoceros gracilis
by: ALBERTA RIKA PRATIWI, et al.
Published: (2009-12-01)

Fatty Acid Synthesis by Indonesian Marine Diatom, Chaetoceros gracilis
by: ALBERTA RIKA PRATIWI, et al.
Published: (2009-12-01)

Plasma Phospholipid <em>n</em>-3/<em>n</em>-6 Polyunsaturated Fatty Acids and Desaturase Activities in Relation to Moderate-to-Vigorous Physical Activity through Pregnancy: A Longitudinal Study within the NICHD Fetal Growth Studies
by: Liwei Chen, et al.
Published: (2020-11-01)

Polyunsaturated fatty acids for multiple sclerosis treatment
by: Monserrat Kong-González, et al.
Published: (2015-01-01)

Neurotropic action of soy lecithin in the process of cognitive function formation in white rats.
by: A. L. Drozdov, et al.
Published: (2015-03-01)

Neurotropic action of soy lecithin in the process of cognitive function formation in white rats
by: Drozdov A.L., et al.
Published: (2015-03-01)

NASH Therapy: omega 3 supplementation, vitamin E, insulin sensitizers and statin drugs
by: Stephen Caldwell
Published: (2017-06-01)

Topical Formulation Comprising Fatty Acid Extract from Cod Liver Oil: Development, Evaluation and Stability Studies
by: Biljana Ilievska, et al.
Published: (2016-06-01)

Omega-3 polyunsaturated fatty acids: Their potential role in blood pressure prevention and management
by: Claudio Borghi, et al.
Published: (2010-05-01)

Conjugated linoleic acid or omega 3 fatty acids increase mitochondrial biosynthesis and metabolism in skeletal muscle cells
by: Vaughan Roger A, et al.
Published: (2012-10-01)

Omega-6 Polyunsaturated Fatty Acids Enhance Tumor Aggressiveness in Experimental Lung Cancer Model: Important Role of Oxylipins
by: Mayra Montecillo-Aguado, et al.
Published: (2022-05-01)

Effect of Omega-3 Rich High-Fat Diet on Markers of Tissue Lipid Metabolism in Glucocorticoid-Treated Mice
by: Wangkuk Son, et al.
Published: (2023-07-01)

Effect of Supplementation with Omega-3 Polyunsaturated Fatty Acids on Metabolic Modulators in Skeletal Muscle of Rats with an Obesogenic High-Fat Diet
by: Mara Patricia Chávez-Ortega, et al.
Published: (2024-02-01)

Hepatic Fasting-Induced PPARα Activity Does Not Depend on Essential Fatty Acids
by: Arnaud Polizzi, et al.
Published: (2016-09-01)

Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue
by: Sebastian Dieckmann, et al.
Published: (2020-02-01)

Important bioactive properties of omega-3 fatty acids
by: Rui Xu
Published: (2015-06-01)

Interactions between Obesity Status and Dietary Intake of Monounsaturated and Polyunsaturated Oils on Human Gut Microbiome Profiles in the Canola Oil Multicenter Intervention Trial (COMIT)
by: Shuaihua Pu, et al.
Published: (2016-10-01)

Assessment of Fatty Acids Profile and Omega-3 Polyunsaturated Fatty Acid Production by the Oleaginous Marine Thraustochytrid <i>Aurantiochytrium</i> sp. T66 Cultivated on Volatile Fatty Acids
by: Alok Patel, et al.
Published: (2020-04-01)

Analysis of polyunsaturated fatty acids in antipsychotic-free individuals with at-risk mental state and patients with first-episode schizophrenia
by: Anh Thi Phuong Le, et al.
Published: (2023-07-01)

Generation of Fad2 and Fad3 transgenic mice that produce n-6 and n-3 polyunsaturated fatty acids
by: Lishuang Song, et al.
Published: (2019-10-01)

The Effect of Ethyl Esters of Linseed Oil on the Changes in the Fatty Acid Profile of Hair Coat Sebum, Blood Serum and Erythrocyte Membranes in Healthy Dogs
by: Anna Wyrostek, et al.
Published: (2023-07-01)

Influence of biostimulants and humic extracts treatment on the fatty acid profile of the spring oilseed rape variety
by: I. Petrova, et al.
Published: (2023-03-01)

Phenotypic convergence in a natural Daphnia population acclimated to low temperature
by: Christian Werner, et al.
Published: (2021-11-01)

The Influence of Probiotic Lactobacilli and Flaxseed on the Health of Weaned Piglets and Metabolism of Polyunsaturated Fatty Acids (PUFAs)
by: Sopková D., et al.
Published: (2016-12-01)

Modulatory Effect of Dietary Polyunsaturated Fatty Acids on Immunity, Represented by Phagocytic Activity
by: Hanan Al-Khalaifah
Published: (2020-09-01)

Effect of dietary polyunsaturated fatty acids and Vitamin E on serum oxidative status in horses performing very light exercise
by: Liviana Prola, et al.
Published: (2010-01-01)

Quantum Yield and Fatty Acid Profile Variations With Nutritional Mode During Microalgae Cultivation
by: M. V. Rohit, et al.
Published: (2018-09-01)