RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons

RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons

Synaptic ribbons are presynaptic specializations that define eponymous ribbon synapses. Synaptic ribbons are largely composed of RIBEYE, a protein containing an N-terminal A-domain and a carboxyterminal B-domain that is identical with CtBP2, a NAD(H)-binding transcriptional co-repressor. Previously...

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Bibliographic Details
Main Authors: Soni Shankhwar, Karin Schwarz, Rashmi Katiyar, Martin Jung, Stephan Maxeiner, Thomas C. Südhof, Frank Schmitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
retina
inner ear
ribbon synapse
synaptic ribbon
RIBEYE A-domain
RIBEYE B-domain
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.838311/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.838311/full

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