How Much Does Thrombocytopenia Affect the Predictive Risk of Mortality Score (Prism Ⅲ) in Critically-ill Children?

Background: The main goal of the pediatric intensive care unit (PICU) is to reduce mortality. PRISM is one of the predictor models of mortality in patients admitted to the PICU. This study aimed to evaluate the effect of thrombocytopenia on the predicted death rate (PDR) in pediatrics admitted to th...

Full description

Bibliographic Details
Main Authors: Somayeh Mohammadpour, Gholamreza Khademi, Maryam Naseri, Majid Khadem Rezaeian, Majid Sezavar
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-01-01
Series:International Journal of Pediatrics
Subjects:
Online Access:https://ijp.mums.ac.ir/article_21592_699be688ce0bf50e3eb525010d4f1261.pdf
_version_ 1797944817169203200
author Somayeh Mohammadpour
Gholamreza Khademi
Maryam Naseri
Majid Khadem Rezaeian
Majid Sezavar
author_facet Somayeh Mohammadpour
Gholamreza Khademi
Maryam Naseri
Majid Khadem Rezaeian
Majid Sezavar
author_sort Somayeh Mohammadpour
collection DOAJ
description Background: The main goal of the pediatric intensive care unit (PICU) is to reduce mortality. PRISM is one of the predictor models of mortality in patients admitted to the PICU. This study aimed to evaluate the effect of thrombocytopenia on the predicted death rate (PDR) in pediatrics admitted to the PICU, by the PRISM scoring system.Methods: This cross-sectional study was performed on patients admitted to the PICU of Akbar Hospital, Mashhad, Iran, from March 2019 to March 2020. Based on the information collected during the first 4 h of patient admission to the PICU, the PRISM score was calculated by the PRISM online calculator. The percentage of PDR calculated for each patient indicated the possibility of patient mortality. Statistical analysis was carried out using SPSS software (Version 25, SPSS Inc., Chicago, IL, USA) at the significant level of α=0.05.Results: The results of the data analysis demonstrated that along with increasing the severity of thrombocytopenia, an increase in the average PDR was observed. Furthermore, the findings revealed a significant correlation between the average PDR and the death of patients.Conclusions: It can be concluded that the effect of thrombocytopenia on mortality is greater than that considered in the PRISM scoring system.
first_indexed 2024-04-10T20:45:38Z
format Article
id doaj.art-30c04b4c0b8649ba80be4f320382cfc8
institution Directory Open Access Journal
issn 2345-5047
2345-5055
language English
last_indexed 2024-04-10T20:45:38Z
publishDate 2023-01-01
publisher Mashhad University of Medical Sciences
record_format Article
series International Journal of Pediatrics
spelling doaj.art-30c04b4c0b8649ba80be4f320382cfc82023-01-24T08:03:55ZengMashhad University of Medical SciencesInternational Journal of Pediatrics2345-50472345-50552023-01-01111172791728510.22038/ijp.2022.68906.510621592How Much Does Thrombocytopenia Affect the Predictive Risk of Mortality Score (Prism Ⅲ) in Critically-ill Children?Somayeh Mohammadpour0Gholamreza Khademi1Maryam Naseri2Majid Khadem Rezaeian3Majid Sezavar4Student research committee, Mashhad University of Medical Sciences, Mashhad, Iran-Neonatal Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. -Clinical Research Development Unit of Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of community medicine and public health, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of pediatrics, Mashhad university of medical sciences,mahshhad,iranBackground: The main goal of the pediatric intensive care unit (PICU) is to reduce mortality. PRISM is one of the predictor models of mortality in patients admitted to the PICU. This study aimed to evaluate the effect of thrombocytopenia on the predicted death rate (PDR) in pediatrics admitted to the PICU, by the PRISM scoring system.Methods: This cross-sectional study was performed on patients admitted to the PICU of Akbar Hospital, Mashhad, Iran, from March 2019 to March 2020. Based on the information collected during the first 4 h of patient admission to the PICU, the PRISM score was calculated by the PRISM online calculator. The percentage of PDR calculated for each patient indicated the possibility of patient mortality. Statistical analysis was carried out using SPSS software (Version 25, SPSS Inc., Chicago, IL, USA) at the significant level of α=0.05.Results: The results of the data analysis demonstrated that along with increasing the severity of thrombocytopenia, an increase in the average PDR was observed. Furthermore, the findings revealed a significant correlation between the average PDR and the death of patients.Conclusions: It can be concluded that the effect of thrombocytopenia on mortality is greater than that considered in the PRISM scoring system.https://ijp.mums.ac.ir/article_21592_699be688ce0bf50e3eb525010d4f1261.pdfintensive care unitmortalityprismpediatric scoring system
spellingShingle Somayeh Mohammadpour
Gholamreza Khademi
Maryam Naseri
Majid Khadem Rezaeian
Majid Sezavar
How Much Does Thrombocytopenia Affect the Predictive Risk of Mortality Score (Prism Ⅲ) in Critically-ill Children?
International Journal of Pediatrics
intensive care unit
mortality
prism
pediatric scoring system
title How Much Does Thrombocytopenia Affect the Predictive Risk of Mortality Score (Prism Ⅲ) in Critically-ill Children?
title_full How Much Does Thrombocytopenia Affect the Predictive Risk of Mortality Score (Prism Ⅲ) in Critically-ill Children?
title_fullStr How Much Does Thrombocytopenia Affect the Predictive Risk of Mortality Score (Prism Ⅲ) in Critically-ill Children?
title_full_unstemmed How Much Does Thrombocytopenia Affect the Predictive Risk of Mortality Score (Prism Ⅲ) in Critically-ill Children?
title_short How Much Does Thrombocytopenia Affect the Predictive Risk of Mortality Score (Prism Ⅲ) in Critically-ill Children?
title_sort how much does thrombocytopenia affect the predictive risk of mortality score prism iii in critically ill children
topic intensive care unit
mortality
prism
pediatric scoring system
url https://ijp.mums.ac.ir/article_21592_699be688ce0bf50e3eb525010d4f1261.pdf
work_keys_str_mv AT somayehmohammadpour howmuchdoesthrombocytopeniaaffectthepredictiveriskofmortalityscoreprismiiiincriticallyillchildren
AT gholamrezakhademi howmuchdoesthrombocytopeniaaffectthepredictiveriskofmortalityscoreprismiiiincriticallyillchildren
AT maryamnaseri howmuchdoesthrombocytopeniaaffectthepredictiveriskofmortalityscoreprismiiiincriticallyillchildren
AT majidkhademrezaeian howmuchdoesthrombocytopeniaaffectthepredictiveriskofmortalityscoreprismiiiincriticallyillchildren
AT majidsezavar howmuchdoesthrombocytopeniaaffectthepredictiveriskofmortalityscoreprismiiiincriticallyillchildren