<it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigs
<p>Abstract</p> <p>Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species. In this study, the polymorphism-based approach was used to detect the imprinting status of <it>...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
BMC
2007-09-01
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| Series: | Genetics Selection Evolution |
| Subjects: | |
| Online Access: | http://www.gse-journal.org/content/39/5/599 |
| Summary: | <p>Abstract</p> <p>Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species. In this study, the polymorphism-based approach was used to detect the imprinting status of <it>NNAT </it>and <it>DIRAS3 </it>genes in five heterozygous pigs (based on SNP) of Large White and Meishan F<sub>1 </sub>hybrids. The results show that both genes were paternally expressed in all the tested tissues (heart, liver, spleen, lung, kidney, stomach, small intestine, skeletal muscle, fat, uterus, ovary and pituitary). In addition, the <it>NNAT </it>gene had two transcripts in all tested tissues, which is consistent with its counterpart in man and cattle.</p> |
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| ISSN: | 0999-193X 1297-9686 |