<it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigs

<p>Abstract</p> <p>Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species. In this study, the polymorphism-based approach was used to detect the imprinting status of <it>...

Full description

Bibliographic Details
Main Authors: Lei Ming-Gang, Li Feng-E, Xiong Yuan-Zhu, Jiang Cao-De, Deng Chang-Yan, Zhang Feng-Wei, Cheng Huan-Chen
Format: Article
Language:deu
Published: BMC 2007-09-01
Series:Genetics Selection Evolution
Subjects:
Online Access:http://www.gse-journal.org/content/39/5/599
_version_ 1819028498518376448
author Lei Ming-Gang
Li Feng-E
Xiong Yuan-Zhu
Jiang Cao-De
Deng Chang-Yan
Zhang Feng-Wei
Cheng Huan-Chen
author_facet Lei Ming-Gang
Li Feng-E
Xiong Yuan-Zhu
Jiang Cao-De
Deng Chang-Yan
Zhang Feng-Wei
Cheng Huan-Chen
author_sort Lei Ming-Gang
collection DOAJ
description <p>Abstract</p> <p>Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species. In this study, the polymorphism-based approach was used to detect the imprinting status of <it>NNAT </it>and <it>DIRAS3 </it>genes in five heterozygous pigs (based on SNP) of Large White and Meishan F<sub>1 </sub>hybrids. The results show that both genes were paternally expressed in all the tested tissues (heart, liver, spleen, lung, kidney, stomach, small intestine, skeletal muscle, fat, uterus, ovary and pituitary). In addition, the <it>NNAT </it>gene had two transcripts in all tested tissues, which is consistent with its counterpart in man and cattle.</p>
first_indexed 2024-12-21T05:59:19Z
format Article
id doaj.art-30c3527497bc4356bbdbfdd9476f4c84
institution Directory Open Access Journal
issn 0999-193X
1297-9686
language deu
last_indexed 2024-12-21T05:59:19Z
publishDate 2007-09-01
publisher BMC
record_format Article
series Genetics Selection Evolution
spelling doaj.art-30c3527497bc4356bbdbfdd9476f4c842022-12-21T19:13:47ZdeuBMCGenetics Selection Evolution0999-193X1297-96862007-09-0139559960710.1186/1297-9686-39-5-599<it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigsLei Ming-GangLi Feng-EXiong Yuan-ZhuJiang Cao-DeDeng Chang-YanZhang Feng-WeiCheng Huan-Chen<p>Abstract</p> <p>Although expression and epigenetic differences of imprinted genes have been extensively characterised in man and the mouse, little is known on livestock species. In this study, the polymorphism-based approach was used to detect the imprinting status of <it>NNAT </it>and <it>DIRAS3 </it>genes in five heterozygous pigs (based on SNP) of Large White and Meishan F<sub>1 </sub>hybrids. The results show that both genes were paternally expressed in all the tested tissues (heart, liver, spleen, lung, kidney, stomach, small intestine, skeletal muscle, fat, uterus, ovary and pituitary). In addition, the <it>NNAT </it>gene had two transcripts in all tested tissues, which is consistent with its counterpart in man and cattle.</p>http://www.gse-journal.org/content/39/5/599pig<it>NNAT</it><it>DIRAS3</it>imprintingpaternally expressed
spellingShingle Lei Ming-Gang
Li Feng-E
Xiong Yuan-Zhu
Jiang Cao-De
Deng Chang-Yan
Zhang Feng-Wei
Cheng Huan-Chen
<it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigs
Genetics Selection Evolution
pig
<it>NNAT</it>
<it>DIRAS3</it>
imprinting
paternally expressed
title <it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigs
title_full <it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigs
title_fullStr <it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigs
title_full_unstemmed <it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigs
title_short <it>NNAT </it>and <it>DIRAS3 </it>genes are paternally expressed in pigs
title_sort it nnat it and it diras3 it genes are paternally expressed in pigs
topic pig
<it>NNAT</it>
<it>DIRAS3</it>
imprinting
paternally expressed
url http://www.gse-journal.org/content/39/5/599
work_keys_str_mv AT leiminggang itnnatitanditdiras3itgenesarepaternallyexpressedinpigs
AT lifenge itnnatitanditdiras3itgenesarepaternallyexpressedinpigs
AT xiongyuanzhu itnnatitanditdiras3itgenesarepaternallyexpressedinpigs
AT jiangcaode itnnatitanditdiras3itgenesarepaternallyexpressedinpigs
AT dengchangyan itnnatitanditdiras3itgenesarepaternallyexpressedinpigs
AT zhangfengwei itnnatitanditdiras3itgenesarepaternallyexpressedinpigs
AT chenghuanchen itnnatitanditdiras3itgenesarepaternallyexpressedinpigs