Multifactorial Pathogenic Processes of Retinal Ganglion Cell Degeneration in Glaucoma towards Multi-Target Strategies for Broader Treatment Effects

Multifactorial Pathogenic Processes of Retinal Ganglion Cell Degeneration in Glaucoma towards Multi-Target Strategies for Broader Treatment Effects

Glaucoma is a chronic neurodegenerative disease characterized by apoptosis of retinal ganglion cell (RGC) somas, degeneration of axons, and loss of synapses at dendrites and axon terminals. Glaucomatous neurodegeneration encompasses multiple triggers, multiple cell types, and multiple molecular path...

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Bibliographic Details
Main Author: Gülgün Tezel
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
glia
glaucoma
immunomodulation
neurodegeneration
neuroinflammation
neuroprotection
Online Access:https://www.mdpi.com/2073-4409/10/6/1372

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